Education, Science, Technology, Innovation and Life
Open Access
Sign In

ChREBP in Response to Carbohydrates in Glucolipid Metabolism of Fish

Download as PDF

DOI: 10.23977/aduhe.2021.030302 | Downloads: 6 | Views: 844

Author(s)

Wenkai Li 1

Affiliation(s)

1 College of Science, Shantou University, Shantou, Guangdong, 515063, China

Corresponding Author

Wenkai Li

ABSTRACT

Protein, as the most important nutrient in fish compound feed, however, due to the limited utilization ability of carbohydrate in fish, fish are "born with diabetes constitution". Inappropriate intake of sugars will disturb the normal glucolipid metabolism of fish and affect the growth and development of fish. Against this background, this review integrates the current research contents on the response of glucolipid metabolism to carbohydrate. Through the role of transcription factors such as ChREBP in carbohydrate, the regulation of related glucolipid metabolic pathways is explained from the perspective of molecular mechanism.

KEYWORDS

ChREBP, Fish, Carbohydrate, Glucolipid metabolism

CITE THIS PAPER

Wenkai Li, Chrebp in Response to Carbohydrates in Glucolipid Metabolism of Fish. Adult and Higher Education (2021) 3: 11-14. DOI: http://dx.doi.org/10.23977/aduhe.2021.030302.

REFERENCES

[1] VSQUEZ TORRES W,ARIAS CASTELLANOS J A. Effect of dietary carbohydrates and lipids on growth in cachama (Piaractus brachypomus) [J]. Aquacult Res,2013,44(11):1768-1776.
[2] Yang Y, Chen L q, LI Y C, et al. Effect of feed sugar level on growth, body composition and serum biochemical indexes of pseudobagrus fulvidraco [J].Journal of Fudan University: Natural Science edition, 2011(05):625-631.
[3] Dou Bing-shuai, Liang Meng-qing, Zheng Keke, et al. Effects of carbohydrate level in feed on growth, physiological parameters and body composition of bass [J].Advances in fishery science, 2014,35 (1) : 46-54.
[4] Hemre G I , Sandnes K , Lie, et al. Carbohydrate nutrition in Atlantic salmon, Salmo salar L.: growth and feed utilization[J]. Aquaculture Research, 2010, 26(3):149-154.
[5] Kristin H . Nutrition in cod (Gadus morhua) larvae and juveniles[J]. Ices Journal of Marine ence, 2006(2):267-274.
[6] Erfanullah, Jafri A K . Growth rate, feed conversion, and body composition of Catla catla, Labeo rohita, and Cirrhinus mrigala fry fed diets of various carbohydrate-to-lipid ratios[J]. J.world Aquacult.soc, 2010, 29(1).
[7] Hemre G I , Mommsen T P , KROGDAHL. Carbohydrates in fish nutrition: effects on growth, glucose metabolism and hepatic enzymes[J]. Aquaculture Nutrition, 2015, 8(3):175-194.
[8] Furuchi, M. & Yone, Y. (1971) Studies on nutrition of red sea bream. 4. Nutritive value of dietary carbohydrate. Rep. Fish. Res. Lab., Kyushu Univ. (Japan), 1, 75–81.
[9] Cowey C B , Adron J W , Brown D A , et al. Studies on the nutrition of marine flatfish. The metabolism of glucose by plaice (Pleuronectes platessa) and the effect of dietary energy source on protein utilization in plaice[J]. British Journal of Nutrition, 1975, 33(2):219-231 [23]Postic C , Dentin R , Denechaud P D , et al. ChREBP, a transcriptional regulator of glucose and lipid metabolism.[J]. Annual Review of Nutrition, 2007, 27(1):179-192.
[10]  G.㊣. Hemre, Kahrs F . 14C‐glucose injection in Atlantic cod, Gadus morhua, metabolic responses and excretion via the gill membrane[J]. Aquaculture Nutrition, 1997, 3(1):3-8.
[11] G‐I. Hemre, Storebakken T . Tissue and organ distribution of 14C‐activity in dextrin‐adapted Atlantic salmon after oral administration of radiolabelled 14C1‐glucose[J]. Aquaculture Nutrition, 2000, 6(4).
[12] Huo Ming, Yang Jichun, Guan Youfei. The role of ChREBP in glycolipid metabolism in hepatocytes [J].Advances in Physiological Science,2009,(4).
[13] Lanaspa M A , Sanchez-Lozada L G , Cicerchi C , et al. Uric Acid Stimulates Fructokinase and Accelerates Fructose Metabolism in the Development of Fatty Liver[J]. Plos One, 2012, 7.
[14] [14] Ma L , Robinson L N , Towle H C . ChREBPMlx Is the Principal Mediator of Glucose-induced Gene Expression in the Liver[J]. Journal of Biological Chemistry, 2006, 281(39):28721.
[15] [15] Dentin R , Pegorier J P , Benhamed F , et al. Hepatic Glucokinase Is Required for the Synergistic Action of ChREBP and SREBP-1c on Glycolytic and Lipogenic Gene Expression[J]. Journal of Biological Chemistry, 2004, 279(19):20314-26.
[16] [16]Savanna. Effects of high-sugar and high-fat diet on liver structure and transcriptome of megalobrama amblycephala growth traits [D].Wuhan: Huazhong Agricultural University,2018.
[17] [17] Tsatsos N G,Towle H C. Glucose activation of ChREBP in hepato-cytes occurs via a two - step mechanism[J].Biochem Biophys Res Commun,2006,340: 449 - 456.
[18] Kim M S , Astapova I I , Flier S N , et al. Intestinal, but not hepatic, ChREBP is required for fructose tolerance[J]. JCI Insight, 2017, 2(24).
[19] Bo C , Yang-Min Z , Jing-Pu Z . Comparative Study of Different Diets-Induced NAFLD Models of Zebrafish[J]. Frontiers in Endocrinology, 2018, 9:366-.
[20] Koo H Y , Miyashita M , Cho B H S , et al. Replacing dietary glucose with fructose increases ChREBP activity and SREBP-1 protein in rat liver nucleus.[J]. Biochemical & Biophysical Research Communications, 2009, 390(2):285-289.

All published work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright © 2016 - 2031 Clausius Scientific Press Inc. All Rights Reserved.