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A Study on the Differences in Adverse Reactions and Reorientation Ability between Right Unilateral and Bilateral Electroconvulsive Therapy for Severe Depressive Disorder

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DOI: 10.23977/medsc.2023.040513 | Downloads: 13 | Views: 399

Author(s)

Tan Pei 1, Li Qiao 2

Affiliation(s)

1 Department of Early Intervention on Mental Illness, Chongqing Mental Health Center, Chongqing, 400020, China
2 Department of Rehabilitation, Chongqing Mental Health Center, Chongqing, 400020, China

Corresponding Author

Tan Pei

ABSTRACT

To investigate the difference of repositioning ability between right and bilateral electroconvulsive therapy in patients with major depression. A total of 40 hospitalized patients with severe depression were randomly divided into right unilateral group (n=20) and bilateral group (n=20).On the basis of original drug treatment, right unilateral and bilateral ECT were administered, respectively. The treatment course was set at 3 times a week for a total of 8 sessions (3 times per week in the first 2 weeks and 2 times in the last week). Both groups also took antidepressants. The Hamilton Depression Rating Scale (HAMD), Hamilton Anxiety Rating Scale (HAMA), Treatment Emergent Symptom Scale (TESS) and clinical observation of adverse reactions were used to evaluate efficacy and safety. The orientation recovery time was tested using an orientation test to study differences in reorientation ability. The study found that both unilateral and bilateral ECT improved symptoms of major depressive disorder. The reduction time after right spasm is shorter than that after bilateral spasm, and the safety is better.

KEYWORDS

Right unilateral, Electroconvulsive therapy, Severe depressive disorder, Orientation

CITE THIS PAPER

Tan Pei, Li Qiao, A Study on the Differences in Adverse Reactions and Reorientation Ability between Right Unilateral and Bilateral Electroconvulsive Therapy for Severe Depressive Disorder. MEDS Clinical Medicine (2023) Vol. 4: 90-94. DOI: http://dx.doi.org/10.23977/medsc.2023.040513.

REFERENCES

[1] Pan Nengrong, Yang Xiaonan, Zhang Chengan, et al. Efficacy of electroconvulsive therapy on depressive disorder [J]. Journal of Clinical Psychiatry, 2015, 15(2):75-77. 
[2] Li Ning, Wang Xueyi, Li Xiaoqian, et al. Randomized controlled trial of repetitive transcranial magnetic stimulation and modified electroconvulsive therapy on the onset time of first-episode depression[J]. Chinese Journal of Mental Health, 2015, 23(9):667-671. 
[3] Zhang Chunping, Huang Xiong, He Hongbo, et al. Correlation between dopamine D2 receptor gene C957T polymorphism and efficacy of modified electroconvulsive therapy in depressive patients [J]. Journal of Practical Medicine, 2013, 29(17):2826-2828. 
[4] Kellner CH, Knapp R, Husain MM, et al. Bifrontal, bitemporal and right unilateral electrode placement in ECT: randomised trial [J]. British Journal of Psychiatry, 2010, 196(3):226-234. doi: 10. 1192/bjp. bp. 109. 066183. 
[5] D'Elia G. Unilateral Electroconvulsive Therapy [J]. Acta Psychiatrica Scandinavica Supplementum, 1970, 215:1-98. 
[6] Kolshus E, Jelovac A, McLoughlin DM. Bitemporal v. high-dose right unilateral electroconvulsive therapy for depression: a systematic review and meta-analysis of randomized controlled trials [J]. Psychological Medicine, 2017, 47(3):518-530. 
[7] Sahlem GL, Short EB, Kerns S, et al. Expanded Safety and Efficacy Data for a New Method of Performing Electroconvulsive Therapy [J]. Journal of ECT, 2016, 32(3):197-203. 
[8] Sackeim HA, Prudic J, Devanand DP, et al. A Prospective, Randomized, Double-blind Comparison of Bilateral and Right Unilateral Electroconvulsive Therapy at Different Stimulus Intensities [J]. Archives of General Psychiatry, 2000, 57(5):425-434. 
[9] Verwijk E, Stek ML, Comijs HC. Relapse and long-term cognitive performance after brief pulse or ultra-brief pulse right unilateral electroconvulsive therapy: A multicenter naturalistic follow-up [J]. Journal of Affective Disorders, 2015, 184:137-144.

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