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  4. Vol 5, Issue 7, 2023

Middle Jiao and IgA Nephropathy

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DOI: 10.23977/medcm.2023.050709 | Downloads: 14 | Views: 357

Author(s)

Yajuan Huang 1, Yun Tian 2

Affiliation(s)

1 Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China
2 Department of Nephrology, Shaanxi Provincial Hospital of Traditional Chinese Medicine, Xi'an, Shaanxi, 710003, China

Corresponding Author

Yun Tian

ABSTRACT

IgA1 (GdIgA1) in the glomerular thylakoid region leads to kidney damage. There is growing evidence that intestinal microecological dysregulation plays a role in the pathogenesis of IgAN. The disease belongs to the category of "oedema," "deficiency labour," and "blood in urine" in Chinese medicine. In recent years, several TCM practitioners have conducted in-depth studies and research from genetics and immunohistology and confirmed that the abnormal immune function of the gastrointestinal mucosa is involved in developing the pathogenesis of IgA nephropathy. Therefore, Chinese medicine in the clinical treatment and prevention of IgAN nephropathy pays much attention to regulating the function of the spleen and stomach in the middle jiao. In this paper, we will study the prevention and treatment of IgA nephropathy from two aspects: the middle jiao and mucosal immunity.

KEYWORDS

IgA nephropathy; mid-focus; mucosal immunity; compartmentalization

CITE THIS PAPER

Yajuan Huang, Yun Tian, Middle Jiao and IgA Nephropathy. MEDS Chinese Medicine (2023) Vol. 5: 63-69. DOI: http://dx.doi.org/10.23977/medcm.2023.050709.

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