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  4. Vol 4, Issue 4, 2023

Study on the Effectiveness of Burdock Root in Weight Loss and Fat Reduction

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DOI: 10.23977/medsc.2023.040418 | Downloads: 12 | Views: 317

Author(s)

Gao Min 1, Yang Wanzhu 2

Affiliation(s)

1 Yunnan Academy of Traditional Chinese Medicine, Kunming 650021, China
2 School of Ethnic Medicine, Yunnan University of Chinese Medicine, Kunming 650500, China

Corresponding Author

Gao Min

ABSTRACT

In order to explore the effect of Burdock roots on fat reduction in obese mice, it was randomly to allote the meal 45 mice C57BL/6J into 5 groups, 9 in each group; The intragastric dose of each group was 16g/(kg•d), 8g/(kg•d, 4g/(kg•d). There were basal feed and fat feed for normal contral group and other 4 groups. Established fat model and used Burdock root for 6 weeks and recorded the weight of the mice weekly. After the sixty weeks, extracted mouse fat, emeasured related experimental indicator. The results manifested that the weight, Lee's index and fat coefficient of the model group were more higher than normal control group. The fat mold was created successfully. Triglyceride (TG), cholesterol (TC), low density lipoprotein cholesterol (LDL-C), Alanine transaminase (ALT)and free fatty acid (FFA) levels of serum had the varying degree to decline. Nevertheless, the high density lipoprotein cholesterol (HDL-C) hasn't increased, Aspartate aminotransferase (AST) and lipase (LPS) were not decline, compared with model group. compared with normal control group, adipocytes’ diameter of model group were increased fat cells' diameter of administration groups were decreased at different level microscopically. It revealed that Burdock roots had certainly effect on lessen weight and lipid lowering effect.

KEYWORDS

Burdock root; weight loss; fat reduction

CITE THIS PAPER

Gao Min, Yang Wanzhu, Study on the Effectiveness of Burdock Root in Weight Loss and Fat Reduction. MEDS Clinical Medicine (2023) Vol. 4: 117-123. DOI: http://dx.doi.org/10.23977/medsc.2023.040418.

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