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The Mechanism and Research Progress of Angelica Sinensis in Preventing and Treating Diabetes Nephropathy

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DOI: 10.23977/medcm.2023.050517 | Downloads: 12 | Views: 385

Author(s)

Ding Yanlin 1, Qu Kai 1, Qi Haiyan 1, Liu Houli 1, Wu Yun 1, Xie Lei 1, Xu Janqin 2

Affiliation(s)

1 Shaanxi University of Traditional Chinese Medicine, Xianyang, 710042, China
2 Shaanxi Academy of Traditional Chinese Medicine, Xi'an, 710003, China

Corresponding Author

Ding Yanlin

ABSTRACT

Diabetes nephropathy is the most important microvascular complication of diabetes, which can eventually progress to end-stage renal disease and affect the quality of life of patients. Traditional Chinese medicine has irreplaceable advantages in the treatment of diabetes and its complications. In recent years, more and more studies have found that angelica sinensis can play a certain role in the prevention and treatment of diabetic nephropathy. The active ingredients of Angelica sinensis can reduce the kidney damage of diabetic nephropathy patients through antiinflammatory, immune enhancement and other functions. It can also play the role of antioxidation, antitissue fibrosis and clearing white group in the local tissue, reduce the changes of kidney hemodynamics and thus reduce the damage caused by hypoxia to kidney tissue. This article reviews the active ingredients of single drug Angelica sinensis, the mechanism of action of Angelica sinensis pair and Angelica sinensis compound in the treatment of diabetes nephropathy and the current research progress, so as to open up new ideas for the treatment of diabetes nephropathy by traditional Chinese medicine.

KEYWORDS

Angelica sinensis, Diabetic nephropathy, Traditional Chinese Medicine

CITE THIS PAPER

Ding Yanlin, Qu Kai, Qi Haiyan, Liu Houli, Wu Yun, Xie Lei, Xu Janqin, The Mechanism and Research Progress of Angelica Sinensis in Preventing and Treating Diabetes Nephropathy. MEDS Chinese Medicine (2023) Vol. 5: 127-133. DOI: http://dx.doi.org/10.23977/medcm.2023.050517.

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