Analysis of the relationship between subclinical hypothyroidism and anxiety and depression based on the theory of

Xinghua Ma; Ji Zeng; Yaling Lei

doi:10.23977/medcm.2023.050515

Analysis of the relationship between subclinical hypothyroidism and anxiety and depression based on the theory of "Yi(liver) and Gui(kidney) from same source"

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DOI: 10.23977/medcm.2023.050515 | Downloads: 11 | Views: 351

Author(s)

Xinghua Ma ¹, Ji Zeng ¹, Yaling Lei ²

Affiliation(s)

¹ Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China
² Shaanxi Provincial Hospital of Chinese Medicine, Xi'an, Shaanxi, 710003, China

Corresponding Author

Yaling Lei

ABSTRACT

For a long time, the influence of subclinical thyroid dysfunction on anxiety and depression has been ignored, and the focus of research is on the influence of obvious thyroid dysfunction on mood. In recent years, the research on the effect of subclinical hypothyroidism on anxiety and depression has gradually increased, and the effect of subclinical hypothyroidism on mood has been re-emphasized. At present, the main measures for clinical diagnosis and treatment of subclinical hypothyroidism in China are clinical observation rather than drug intervention. In fact, patients do have negative emotional changes, which seriously affect people's sleep, study and work. Therefore, in this context, the advantages of traditional Chinese medicine are highlighted again. This paper aims to explore the essence of the relationship between subclinical hypothyroidism (SCH) and anxiety and depression based on the theory of "Yigui homology", so as to provide clinical diagnosis and treatment ideas.

KEYWORDS

Subclinical Hypothyroidism; Anxietyz; Depression

CITE THIS PAPER

Xinghua Ma, Ji Zeng, Yaling Lei, Analysis of the relationship between subclinical hypothyroidism and anxiety and depression based on the theory of "Yi(liver) and Gui(kidney) from same source". MEDS Chinese Medicine (2023) Vol. 5: 112-120. DOI: http://dx.doi.org/10.23977/medcm.2023.050515.

REFERENCES

[1] Shan Z, Chen L, Lian X, et al. Iodine Status and Prevalence of Thyroid Disorders after Introduction of Mandatory Universal Salt Iodization for 16 Years in China: A Cross-Sectional Study in 10 Cities[J]. Thyroid Official Journal of the American Thyroid Association, 2016:1125.
[2] Bernal J. Action of thyroid hormone in brain [J]. Endocrinol.Invest,25:268-288,2002.
[3] Engum A, Bjøro T, Mykletun A, Dahl AA. An association between depression, anxiety and thyroid function--a clinical fact or an artefact? [J]. Acta Psychiatr Scand. 2002; 106(1):27-34.
[4] Zhao T, Chen BM, Zhao XM, Shan ZY. Subclinical hypothyroidism and depression: a meta-analysis [J]. Transl Psychiatry. 2018;8(1):239.
[5] Wildisen L, Del Giovane C, Moutzouri E, et al. An individual participant data analysis of prospective cohort studies on the association between subclinical thyroid dysfunction and depressive symptoms[J]. Sci Rep. 2020;10(1):19111.
[6] Li RC, Zhang L, Luo H, et al. Subclinical hypothyroidism and anxiety may contribute to metabolic syndrome in Sichuan of China: a hospital-based population study[J]. Sci Rep. 2020;10(1):2261.
[7] Boelaert K, Franklyn JA. Thyroid hormone in health and disease. J Endocrinol. 2005;187(1):1-15.
[8] Davis JD, Tremont G. Neuropsychiatric aspects of hypothyroidism and treatment reversibility.. Minerva Endocrinol. 2007;32(1):49-65.
[9] Samuels MH. Subclinical Hypothyroidism and Depression: Is There a Link?. J Clin Endocrinol Metab. 2018; 103(5): 2061-2064.
[10] Vishnoi G, Chakraborty B, Garda H, Gowda SH, Goswami B. Low mood and response to Levothyroxine treatment in Indian patients with subclinical hypothyroidism. Asian J Psychiatr. 2014;8:89-93.
[11] Wildisen L, Feller M, Del Giovane C, et al. Effect of Levothyroxine Therapy on the Development of Depressive Symptoms in Older Adults With Subclinical Hypothyroidism: An Ancillary Study of a Randomized Clinical Trial. JAMA Netw Open. 2021;4(2):e2036645. Published 2021 Feb 1.
[12] Raza SA, Mahmood N. Subclinical hypothyroidism: Controversies to consensus. Indian J Endocrinol Metab. 2013; 17(Suppl 3): S636-S642.
[13] Loh HH, Lim LL, Yee A, Loh HS. Association between subclinical hypothyroidism and depression: an updated systematic review and meta-analysis. BMC Psychiatry. 2019;19(1):12. Published 2019 Jan 8.
[14] Demartini B, Ranieri R, Masu A, Selle V, Scarone S, Gambini O. Depressive symptoms and major depressive disorder in patients affected by subclinical hypothyroidism: a cross-sectional study. J Nerv Ment Dis. 2014;202(8):603-607.
[15] Chueire VB, Romaldini JH, Ward LS. Subclinical hypothyroidism increases the risk for depression in the elderly. Arch Gerontol Geriatr 2007;44:21–8.
[16] Almeida C, Brasil MA, Costa AJ, et al. Subclinical hypothyroidism:psychiatric disorders and symptoms. Rev Bras Psiquiatr 2007;29:157–9.
[17] Feng Min, Gu Chengmin, Chen Yanhua, Fang Jinhong, Lou Juan. Effects of subclinical hypothyroidism on anxiety and depression of pregnant women and neonates [J]. International Journal of Psychiatry, 2017, 44 (06): 1048-1050.
[18] Li Peixuan, Liu Zijian, Teng Yuzhu, Han Yan, Yan Shuangqin, Xu Yeqing,Tao Fangbiao, Huang Kun.Maternal subclinical hypothyroidism and behavioral problems in preschoolers:A cohort study[J]. Chinese Journal of Endocrinology and Metabolism, 2022,38(6):495-502
[19] Wu Zhiguo. Study on clinical features and treatment outcome of anxiety related depressive disorder [D]. Shanghai Jiaotong University, 2015.
[20] De Graaf R, Bijl RV, Smit F, et al. Risk factors for 12 - month comorbidity of mood, anxiety, and substance use disorders: findings from the Netherlands Mental Health Survey and Incidence Study [J].Am J Psychiatry,2002,159( 4) : 620 - 629.
[21] Stein DJ. Comorbidity in generalized anxiety disorder: impact and implications[J].J Clin Psychiatry,2001,62( Suppl 11) : 29-34.
[22] Rosolová H,Podlipny J. Anxious - depressive disorders and metabolic syndrome[J].Vnitr Lek,2009,55( 7 - 8) : 650 - 652.
[23] Yu Xiaoqiang, Li Songmei. A review of modern research on liver controlling dispersion [J]. World Journal of Integrated Traditional and Western Medicine, 2012, 7 (9): 817-819.
[24] Yan Can, Xu Zhiwei. Exploration on Central Neurobiological Mechanisms of Gan in Taking Charge of Dispersion and Regulating Emotion [J]. Chinese Journal of Integrated Traditional and Western Medicine, 2005,25(5):459-462.
[25] Shen Yan, Kuang Tiaoyuan. An Experimental Research on a Theory of "fright injuring kidney" [J]. China Journal of Traditional Chinese Medicine and Pharmacy, 1991,6(1):13-1664.
[26] Qi Xiaohua, Shen Meihong. Preliminary Approach to Relationship between acupuncture Promoting Fracture Union and the Kidney Being in Charge of the Bone[J]. Chinese Acuponcture & Moxibustion, 1999, (12): 747 1999,19(12):747-750.
[27] Shen Ziyin. Rule of tonifying the kidney in regulating T lymphocyte apoptosis in syndrome of kidney-yang deficiency--plasticity of gene balance [J]. Journal of Chinese Integrative Medicine, 2004,2(5):321-322.
[28] Shen Ziyin. Contemplation and Practice on Research from Kidney Essence to Syndrome Essence ——Promotion of Mutual Supplement of Chinese and Western Medicines to a Higher Level by Research on Integration of Chinese and Wes [J]. Shanghai Journal Of Traditional Chinese Medicine, 2000,34(4):4-7.
[29] Fang Bei. Clinical Study on Treatment of PCOS with SCH by Xie He Yin [D]. Nanjing University of Chinese Medicine, 2021.
[30] Li Yongle. Multiple Relationship Between the Liver and Emotions in the Inner Canon of Huangdi [J]. Journal of Basic Chinese Medicine, 2016,22(2):154-155.
[31] Zhang Juan, Wang Xiaoping. New Explanation of “the Liver Being the Root of Exhaustion”[J]. Journal of Shandong University of Traditional Chinese Medicine, 2021,45(4):444-448.
[32] Jiang Ganjin. Medical Psychology [M]. 4th Edition. Beijing: People's Medical Publishing House, 2004: 48-49.

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Analysis of the relationship between subclinical hypothyroidism and anxiety and depression based on the theory of "Yi(liver) and Gui(kidney) from same source"

Author(s)

Affiliation(s)

Corresponding Author

ABSTRACT

KEYWORDS

CITE THIS PAPER

REFERENCES

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