Correlation between handgrip strength and nutritional indicators and its influencing factors in patients with stable COPD: a cross-sectional study
DOI: 10.23977/medsc.2023.040408 | Downloads: 4 | Views: 155
Yue'e Ma 1, Miaoling Cui 1, Qingmei Chen 1, Diandian Jiang 2, Zhenjiao Yang 2
1 Department of Nursing, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530021, China
2 Department of Respiratory Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530021, China
Corresponding AuthorMiaoling Cui
This study aimed to explore the Correlation between handgrip strength and nutritional indicators and its influencing factors in patients with stable chronic obstructive pulmonary disease (COPD) to provide evidence for early nutritional intervention. Stable COPD patients who visited the respiratory department clinic of a Tertiary Grade A hospital in Guangxi from January 2021 to March 2022 were chosen using a convenient sampling method. The general information questionnaire and mini nutritional assessment short-form (MNA-SF) were used for investigation, and the HGS, anthropometric, and laboratory indicators were collected. Correlation analysis was used to analyze the relationship between HGS and nutritional indicators in patients with stable COPD. Multiple linear regression analysis was used to examine the factors influencing HGS in patients with stable COPD. A total of 232 patients with stable COPD were included, and the HGS was (25.18±7.95)kg. Correlation analysis showed that height, body weight, body mass index (BMI), calf circumference, hemoglobin concentration, total protein concentration, albumin concentration, prealbumin concentration were positively correlated with HGS in stable COPD patients (P <0.05), whereas age was negatively correlated with HGS in stable COPD patients (P <0.05). Multiple linear regression analysis showed that gender, age, number of concomitant diseases, and nutritional status were the influencing factors of HGS in patients with stable COPD (P <0.05), explaining 31.3% of the total variation of HGS in patients with stable COPD. Patients with stage COPD need to improve their HGS, which correlates with nutrition-related indicators. HGS levels are low in female COPD patients who are older, have multiple comorbidities, and are malnourished. Outpatient medical workers should pay attention to the HGS level of stable COPD patients, quickly screen the nutritional status of COPD patients, implement early nutritional intervention, and improve the overall health level of patients.
KEYWORDSPulmonary disease, Chronic obstructive, Handgrip strength, Nutrition, Analysis of influencing factors
CITE THIS PAPER
Yue'e Ma, Miaoling Cui, Qingmei Chen, Diandian Jiang, Zhenjiao Yang, Correlation between handgrip strength and nutritional indicators and its influencing factors in patients with stable COPD: a cross-sectional study. MEDS Clinical Medicine (2023) Vol. 4: 53-60. DOI: http://dx.doi.org/10.23977/medsc.2023.040408.
 Zhou M, Wang H, Zeng X, et al. Mortality, morbidity, and risk factors in China and its provinces, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017[J]. Lancet, 2019, 394(10204):1145-1158.
 Nguyen H T, Collins P F, Pavey T G, et al. Nutritional status, dietary intake, and health-related quality of life in outpatients with COPD[J]. Int J Chron Obstruct Pulmon Dis, 2019, 14:215-226.
 Tao Y, Guo H H, Zhang C H. Recent advances in pathogenesis and nutrition interventions of frailty in chronic obstructive pulmonary disease [J]. ChineseGeneral Practice, 2021, 24(6):684-689.
 Alima1, Yang F, Xu M Y, et al. Analysis of nutritional status of 542 hospitalized patients with chronic respiratory diseases [J]. Parenteral & Enteral Nutrition, 2021, 28(01):16-20.
 Dou B, Liu K Y, Tang Ting, et al. Research progress on the effectiveness of nutrition evaluation in patients with COPD [J]. Parenteral & Enteral Nutrition, 2020, 27(04):248-253.
 Reeve T T, Craven T E, Goldman M P, et al. Outpatient grip strength measurement predicts survival, perioperative adverse events, and nonhome discharge among patients with vascular disease [J]. J Vasc Surg, 2021, 73(1):250-257.
 Wu Z Y, Niu M E, Han Y X, et al. Application of handgrip strength test for evaluating mobility in patients with stable chronic obstructive pul-monary disease[J]. Chinese Journal of Nursing, 2017, 52(08):926-929.
 Holden M, Fyfe M, Poulin C, et al. Handgrip Strength in People With Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis[J]. Phys Ther, 2021, 101(6).
 Lv G L, Zhou T T, Xi H L, et al. Predictive value of grip strength for nutritional status in peritoneal dialysis patients[J]. Parenteral & Enteral Nutrition, 2020, 27(06):358-362.
 Ma X, Zhang Y P, Xie B, et al. Status and influencing factors of grip strength in elderly patients with mechanical ventilation in lCU [J]. Chinese Journal of Nursing, 2022, 57(03):279-284.
 Global Initiative for Chronic Lung Disease (GOLD). Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease 2020 report[EB/OL]. (2019-11-05) [2021-10-6]https://goldCOPD. org/gold-reports/.
 Rubenstein L Z, Harker J O, Salva A, et al. Screening for undernutrition in geriatric practice: developing the short-form mini-nutritional assessment (MNA-SF)[J]. J Gerontol A Biol Sci Med Sci, 2001, 56(6):M366-M372.
 Byun M K, Cho E N, Chang J, et al. Sarcopenia correlates with systemic inflammation in COPD[J]. Int J Chron Obstruct Pulmon Dis, 2017, 12:669-675.
 Bui K L, Nyberg A, Rabinovich R, et al. The Relevance of Limb Muscle Dysfunction in Chronic Obstructive Pulmonary Disease: A Review For Clinicians [J]. Clin Chest Med, 2019, 40(2):367-383.
 Wu Z Y, Niu M E, Han Y X , et al. Status quo of grip strength of patients with stable chronic obstructive pulmonary disease and its influencing factors[J]. Chinese Nursing research, 2018, 32(19):3046-3049.
 Alison J A. Handgrip strength: potential of a simple test to aid management in chronic obstructive pulmonary disease [J]. Int J Tuberc Lung Dis, 2019, 23(4):385-386.
 Ahmadi A, Mazloom Z, Eftekhari M H, et al. Muscle mass and function are related to respiratory function in chronic obstructive pulmonary disease[J]. Med J Islam Repub Iran, 2021, 35:34.
 Lu X, Chu H, Wang L, et al. Age- and sex-related differences in muscle strength and physical performance in older Chinese[J]. Aging Clin Exp Res, 2020, 32(5):877-883.
 Celis-Morales C A, Welsh P, Lyall D M, et al. Associations of grip strength with cardiovascular, respiratory, and cancer outcomes and all cause mortality: prospective cohort study of half a million UK Biobank participants[J]. BMJ, 2018, 361:k1651.
 Zasadzka E, Pieczynska A, Trzmiel T, et al. Correlation between Handgrip Strength and Depression in Older Adults-A Systematic Review and a Meta-Analysis[J]. Int J Environ Res Public Health, 2021, 18(9).
 Kwak Y, Kim Y, Chung H. Sex-Associated Differences in the Handgrip Strength of Elderly Individuals[J]. West J Nurs Res, 2020, 42(4):262-268.
 Montalcini T, Migliaccio V, Ferro Y, et al. Androgens for postmenopausal women's health?[J]. Endocrine, 2012, 42(3): 514-520.
 Wu H, Liu M, Zhang Q, et al. Reference values for handgrip strength: data from theTianjin Chronic Low-Grade Systemic Inflammation and Health (TCLSIH) cohort study[J]. Age Ageing, 2020, 49(2):233-238.
 Yang Y F. Correlation analysis of grip strength, walking speed and bone mineral density in elderly men[D]. Xinjiang Medical University, 2020.
 Montes M C, Bortolotto C C, Tomasi E, et al. Strength and multimorbidity among community-dwelling elderly from southern Brazil[J]. Nutrition, 2020, 71:110636.
 Triest F, Franssen F, Reynaert N, et al. Disease-Specific Comorbidity Clusters in COPD and Accelerated Aging[J]. J Clin Med, 2019, 8(4).
 Dong X Y, Zhang L J, Gu D H, et al. Longitudinal Study of the Association Between Handgrip Strength and Chronic Disease Multimorbidity among Middle-aged and Older Adults[J]. Journal of Sichuan University (Medical Edition), 2021, 52(02): 267-273.
 Raad S, Smith C, Allen K. Nutrition Status and Chronic Obstructive Pulmonary Disease: Can We Move Beyond the Body Mass Index?[J]. Nutr Clin Pract, 2019, 34(3):330-339.
 Sun W W. The Effect of Nutritional Status on PatientsWith Stable Chronic Obstructive Pulmonary Disease[D]. Ningxia Medical University, 2021.
 Deutz N E, Ziegler T R, Matheson E M, et al. Reduced mortality risk in malnourished hospitalized older adult patients with COPD treated with a specialized oral nutritional supplement: Sub-group analysis of the NOURISH study[J]. Clin Nutr, 2021, 40(3):1388-1395.
 Liu F, Xu M L. The effect of noninvasive positive pressure ventilation combined with sequential enteral and parenteral nutrition support on severe malnutrition in elderly patients with acute exacerbation of COPD complicated with respiratory failure[J]. Chinese Journal of Gerontology, 2021, 41(19):4221-4224.
 Qaisar R, Karim A, Muhammad T. Circulating Biomarkers of Handgrip Strength and Lung Function in Chronic Obstructive Pulmonary Disease[J]. Int J Chron Obstruct Pulmon Dis, 2020, 15:311-321.
 Chen R, Xing L, You C, et al. Prediction of prognosis in chronic obstructive pulmonary disease patients with respiratory failure: A comparison of three nutritional assessment methods[J]. Eur J Intern Med, 2018, 57:70-75.
 Zhang H H, Wang C P, Zhao M, et al. Mini-Nutritional Assessment and Short-Form Mini-Nutritional Assessment in evaluating nutritional status of the elderly in community[J]. Journal of Shandong University (Medical Edition), 2017, 55(11): 65-70.
 Chen X, Zhang Y X. Research progress of grip strength measurement in nutritional assessment of patients with liver diseases[J]. Chinese Journal of Nursing, 2017, 52(04):469-473.