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Unlocking the power of G-quadruplex for anti-HIV1 development

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DOI: 10.23977/medsc.2023.040407 | Downloads: 14 | Views: 429

Author(s)

Kaihong Ooi 1, Yu Qi 2

Affiliation(s)

1 University of Malaya, Kuala Lumpur, Malaysia
2 University of Sanya, Sanya, China

Corresponding Author

Kaihong Ooi

ABSTRACT

The role of G-quadruplexes (GQP) in the life cycle of other viruses has led to the speculation that they may also have a function in the HIV genome. This paper aims to write-up on the potential of G-quadruplex as a potential anti-viral development. This paper narrates on (1) innovation of G-quadruplex detector, (2) location of G-quadruplex in HIV genome, (3) evidence and therapeutic approach using GQP as anti-HIV, and (4) contradiction on G-quadruplex utilization. The results of this investigation offer a quick insight on the use of G-quadruplex as a target and highlighting the potential of such intervention for antiviral treatments.

KEYWORDS

G-quadruplex; HIV-1; Antiviral development; GQP ligands

CITE THIS PAPER

Kaihong Ooi, Yu Qi, Unlocking the power of G-quadruplex for anti-HIV1 development. MEDS Clinical Medicine (2023) Vol. 4: 49-52. DOI: http://dx.doi.org/10.23977/medsc.2023.040407.

REFERENCES

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