Education, Science, Technology, Innovation and Life
Open Access
Sign In

Progress in the Treatment of Motor Neurone Disease with Traditional Chinese and Western Medicine

Download as PDF

DOI: 10.23977/medsc.2023.040402 | Downloads: 9 | Views: 401


Yanhong Liu 1, Bingcang Yan 2


1 Shaanxi University of Traditional Chinese Medicine, Xianyang, Shaanxi, 712046, China
2 Xi'an Traditional Chinese Medicine Encephalopathy Hospital, Xi'an, Shaanxi, 710068, China

Corresponding Author

Yanhong Liu


Motor neurone disease (MND) is commonly referred to as amyotrophic lateral sclerosis, which is characterized by progressive muscle weakness and muscle atrophy. At present, Western medicine has limited effective treatment measures for motor neurone disease. A large number of clinical trials have proved that TCM has achieved obvious curative effect in the treatment of MND through dialectical treatment, which can alleviate the clinical symptoms of patients to a certain extent. Therefore, this paper further discusses the progress of TCM and western medicine in the treatment of MND.


Motor neuropathy, traditional Chinese medicine, treatment


Yanhong Liu, Bingcang Yan, Progress in the Treatment of Motor Neurone Disease with Traditional Chinese and Western Medicine. MEDS Clinical Medicine (2023) Vol. 4: 8-14. DOI:


[1] Leigh, P N. The management of motor neurone disease[J]. J Neurol Neurosurg Psychiatry, 2003, 74(90004):iv32.
[2] Zhou Shiyuan, Current status of TCM research and treatment of motor neurone disease. China Journal of Traditional Chinese Medicine, 2018, (06):2468-2471.
[3] Wang Xiaoyan. Study on distribution law of TCM syndrome of Motor Neurone disease [C]. Guangzhou University of Traditional Chinese Medicine, 2007.
[4] Shang Cong, Hai Y. Discussion on the pathogenesis and treatment of motor neurone disease [J]. Asian-pacific Traditional Medicine, 2019, 15(03):194-197. 
[5] Young C A. Building a care and research team - Journal of the Neurological Sciences[J]. Journal of the Neurological Sciences, 1998, 160 suppl 1(5):S137-40.
[6] Kiernan M C. Riluzole: a glimmer of hope in the treatment of motor neurone disease[J]. Medical Journal of Australia, 2005, 182(7):319-320.
[7] Abbott, Belinda, M, et al. Recent progress towards an effective treatment of amyotrophic lateral sclerosis using the SOD1 mouse model in a preclinical setting[J]. European Journal of Medicinal Chemistry: Chimie Therapeutique, 2016, 121:918-925.
[8] Weifeng wang, Hongyun Chen, Wu Jitao. Experience of Professor Zhai Lei in TCM treatment of motor neurone disease [J]. China Prescription Drugs, 2016, (03):86-87.
[9] Sheers N, Howard M, Hannan L M, et al. P132 Research in the time of COVID-19: Recruitment to a clinical trial comparing models of NIV implementation in people with MND[J]. Sleep Advances, 2021.
[10] O'Brien, Mary, R. Healthcare professionals' knowledge of motor neurone disease.[J]. British Journal of Nursing, 2004.
[11] Gao Lin, Liao Weilong, Sun Chuanhe, Jiang Wenfei, Pan W D. Lianshenfengxin Decoction improves salivation and nocturia in motor neurone disease: a randomized open controlled trial [J]. Journal of Neurology and Neurorehabilitation, 2017, 13(01):10-16.
[12] Zheng Yulin, Wang Baoliang. Wang Baoliang's treatment of motor neurone disease [J]. Clinical Research of Traditional Chinese Medicine, 2014, (01):70-71.
[13] Wang Wenjie. Clinical study of Jiweiling injection in the treatment of motor neurone disease [J]. Journal of Clinical Medical Literature Electronic, 2014, (08):1337+1339.
[14] Zhang Nan. Effects of Shenmai injection in the adjuvant treatment of motor neurone disease with amyotrophic lateral sclerosis [J]. China Minkang Medical, 2020, (08):49-50.
[15] Bywater J, Butt J, Mathias C, et al. P158 A hospice motor neurone disease clinic: challenges and benefits of a new service[J]. Bmj Support Palliat Care, 2013, 3(Suppl 1):A66.1-A66.
[16] Young C A, Tedman B M, Williams I R. Disease progression and perceptions of health in patients with motor neurone disease[J]. 1995, 129(supp-S):50-53.
[17] Hilton J B, Kai K, White A R, et al. The accumulation of enzymatically inactive cuproenzymes is a CNS-specific phenomenon of the SOD1G37R mouse model of ALS and can be restored by overexpressing the human copper transporter hCTR1.[J]. Experimental Neurology, 2018, 307:118-128.
[18] Zhou Shiyuan, Shi Xuemin. Introduction of Academician Shi Xuemin's experience in acupuncture treatment of motor neurone disease. Shanghai Journal of Acupuncture and Moxibustion, 2017, (11):1372-1375.
[19] Yang Y. Progress in clinical treatment of motor neurone disease [J]. Medical Equipment, 2019, 32(04):203-204. 
[20] Rowe D, Erjavec S. An open-label pilot study of intra-parotid botulinum toxin A injections in the treatment of sialorrhea in motor neuron disease. 2003.

Downloads: 5185
Visits: 241121

Sponsors, Associates, and Links

All published work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright © 2016 - 2031 Clausius Scientific Press Inc. All Rights Reserved.