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A review of neuroprotective mechanisms of dexmedetomidine

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DOI: 10.23977/medsc.2023.040113 | Downloads: 11 | Views: 368


Wenxian An 1, Yaying Xie 2


1 Department of Anesthesiology, Inner Mongolia Medical University, Hohhot, China
2 Department of Anesthesiology, the First Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China

Corresponding Author

Wenxian An


Dexmedetomidine (DEX) is a highly specific and effective α2-adrenergic receptor agonist. Due to its high protein binding rate, intravenous pumping can play a good role in sedation and hypnosis, analgesia, anti-anxiety, reducing inflammation, and so on, so it has been widely used in clinical anesthesia and basic research. In recent years, with the further study of dexmedetomidine, it has been found that it has a certain protective effect on nerve injury caused by various causes.


Dexmedetomidine, Neuroprotection, Mechanism, α2-adrenergic Receptor Agonist


Wenxian An, Yaying Xie, A review of neuroprotective mechanisms of dexmedetomidine. MEDS Clinical Medicine (2023) Vol. 4: 78-86. DOI:


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