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Advances in the pharmacological mechanism of Angelica sinensis in the treatment of ischemic stroke

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DOI: 10.23977/medcm.2023.050106 | Downloads: 12 | Views: 510

Author(s)

Zhang Hongyu 1, Chao Chenlin 1, Chen Jie 2

Affiliation(s)

1 Shaanxi University of Chinese Medicine, Xianyang, 712046, China
2 Department of Encephalopathy, Shaanxi Provincial Hospital of Traditional Chinese Medicine, Xi'an, Shaanxi, 710003, China

Corresponding Author

Chen Jie

ABSTRACT

Ischemic stroke is characterized by high lethality and disability, and is currently a serious threat to human health. By collecting and summarizing the medication patterns of several masters of national medicine such as Zhou Zhongying, Deng Tietao and other medical practitioners in the treatment of ischemic stroke and related clinical studies, the author found that Angelica sinensis is one of the most frequently used herbs in clinical practice. In addition, current studies have shown that angelica has anti-inflammatory, anti-platelet aggregation, anti-oxidative stress, anti-atherosclerosis, promotes angiogenesis, reduces cerebral infarct size, regulates blood pressure, and other therapeutic and preventive effects on ischemic strokes. Thus, it can be seen that Angelica has the potential ability and development prospect for the treatment of ischemic stroke that should not be underestimated. In this paper, we summarize the pharmacological mechanism of Angelica sinensis in the treatment of ischemic stroke in order to provide reference for the clinical application of Angelica sinensis.

KEYWORDS

Angelica; ischemic stroke; pharmacological mechanism

CITE THIS PAPER

Zhang Hongyu, Chao Chenlin, Chen Jie, Advances in the pharmacological mechanism of Angelica sinensis in the treatment of ischemic stroke. MEDS Chinese Medicine (2023) Vol. 5: 40-47. DOI: http://dx.doi.org/10.23977/medcm.2023.050106.

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