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The role of the PCSK9 gene in atherosclerotic plaque based on public database and experimental verification

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DOI: 10.23977/medsc.2023.040109 | Downloads: 23 | Views: 442


Hong Wang 1, Bin Li 1, Gaoming Hong 2, Shengqiang Zeng 1, Wenyan Xu 1,3, Liu Yang 1


1 Department of Cardiology, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, 330006, China
2 The People's Hospital of Yujiang District, Yingtan, Jiangxi, 335000, China
3 Medical College of Nanchang University, Nanchang, Jiangxi, 330006, China

Corresponding Author

Liu Yang


Objective: PCSK9 is a protein-coding gene which has been implicated in the formation of atherosclerotic plaques in related studies. Nevertheless, there is limited research on the manifestation of it in atherosclerosis and the underlying mechanisms. Data mining and experimental verification were used to ascertain the expression level of this study in the atherosclerosis rat model.


PCSK9, atherosclerosis, gene expression, data mining


Hong Wang, Bin Li, Gaoming Hong, Shengqiang Zeng, Wenyan Xu, Liu Yang, The role of the PCSK9 gene in atherosclerotic plaque based on public database and experimental verification. MEDS Clinical Medicine (2023) Vol. 4: 53-58. DOI:


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