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The role of the PCSK9 gene in atherosclerotic plaque based on public database and experimental verification

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DOI: 10.23977/medsc.2023.040109 | Downloads: 23 | Views: 442

Author(s)

Hong Wang 1, Bin Li 1, Gaoming Hong 2, Shengqiang Zeng 1, Wenyan Xu 1,3, Liu Yang 1

Affiliation(s)

1 Department of Cardiology, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, 330006, China
2 The People's Hospital of Yujiang District, Yingtan, Jiangxi, 335000, China
3 Medical College of Nanchang University, Nanchang, Jiangxi, 330006, China

Corresponding Author

Liu Yang

ABSTRACT

Objective: PCSK9 is a protein-coding gene which has been implicated in the formation of atherosclerotic plaques in related studies. Nevertheless, there is limited research on the manifestation of it in atherosclerosis and the underlying mechanisms. Data mining and experimental verification were used to ascertain the expression level of this study in the atherosclerosis rat model.

KEYWORDS

PCSK9, atherosclerosis, gene expression, data mining

CITE THIS PAPER

Hong Wang, Bin Li, Gaoming Hong, Shengqiang Zeng, Wenyan Xu, Liu Yang, The role of the PCSK9 gene in atherosclerotic plaque based on public database and experimental verification. MEDS Clinical Medicine (2023) Vol. 4: 53-58. DOI: http://dx.doi.org/10.23977/medsc.2023.040109.

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