Author(s)

Runbing Liu ¹, Xiaohong Zhang ^1,2, Wei Zheng ², Zongqiang Wang ³, Meng Bi ⁴

Affiliation(s)

¹ Zunyi Medical University, Zunyi, 563000, China
² Department of Emergency Medicine, Sichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital, Affiliated Hospital of University of Electronic Science and Technology, Chengdu, 610072, China
³ North Sichuan Medical College, Nanchong, 637000, China
⁴ Chengdu University of Traditional Chinese Medicine, Chengdu, 610072, China

Corresponding Author

Xiaohong Zhang

ABSTRACT

This paper collects clinical data from a patient with novel coronavirus pneumonia combined with left heart failure and a patient with severe novel coronavirus pneumonia living in a highland area. We analyzed the difference between the clinical treatment of novel coronavirus pneumonia combined with left heart failure cardiogenic shock and the clinical treatment of severe novel coronavirus pneumonia. The results showed that patients with combined left heart failure presented with typical patchy shadows in both lungs, bilateral pleural effusion, increased BNP, and a minimum partial pressure of oxygen of 48 mmHg at rest, which was converted to negative nucleic acid after antiviral, oxygen therapy, and cardiac diuresis; patients with severe novel coronavirus pneumonia had hemoptysis, multilobar patchy shadows in both lungs, massive ground glass shadows, adjacent pleural adhesions, and no pleural fluid. After oxygen therapy, antiviral drugs and hormone therapy, the patient's SPO2 increased to more than 90%, the pulmonary ground glass shadow was absorbed, and the nucleic acid turned negative. Patients with high altitude severe novel coronavirus pneumonia compared to patients with novel coronavirus pneumonia combined with left heart failure because of more severe hypoxemia due to alveolar exudation, and novel coronavirus pneumonia combined with left heart failure aggravated the severity of the disease. The increased number of hematologic tests, imaging tests, rapid diagnosis and treatment early intervention can reduce mortality in patients with severe novel coronavirus pneumonia.

KEYWORDS

Novel coronavirus, Pneumonia, Left heart failure

CITE THIS PAPER

Runbing Liu, Xiaohong Zhang, Wei Zheng, Zongqiang Wang, Meng Bi, Comparison of novel coronavirus pneumonia combined with left heart failure and heavy neocoronary pneumonia in highland snowy areas. MEDS Clinical Medicine (2023) Vol. 4: 33-39. DOI: http://dx.doi.org/10.23977/medsc.2023.040106.

REFERENCES

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[3] Pena, E., Brito, J., El Alam, S., & Siques, P. (2020). Oxidative Stress, Kinase Activity and Inflammatory Implications in Right Ventricular Hypertrophy and Heart Failure under Hypobaric Hypoxia. International journal of molecular sciences, 21(17), 6421. 
[4] Perez-Nieto, O. R., Escarraman-Martinez, D., Guerrero-Gutierrez, M. A., Zamarron-Lopez, E. I., Mancilla-Galindo, J., Kammar-García, A., Martinez-Camacho, M. A., Deloya-Tomás, E., Sanchez-Díaz, J. S., Macías-García, L. A., Soriano-Orozco, R., Cruz-Sánchez, G., Salmeron-Gonzalez, J. D., Toledo-Rivera, M. A., Mata-Maqueda, I., Morgado-Villaseñor, L. A., Martinez-Mazariegos, J. J., Flores Ramirez, R., Medina-Estrada, J. L., Ñamendys-Silva, S. A., … APRONOX Group (2022). Awake prone positioning and oxygen therapy in patients with COVID-19: the APRONOX study. The European respiratory journal, 59(2), 2100265. 
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