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Progress in the relationship between each components of metabolic syndrome and glutamate aminotransferase

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DOI: 10.23977/medsc.2023.040102 | Downloads: 9 | Views: 467

Author(s)

Qi Mao 1, Hui Ding 2, Yi Zhou 2, Jian Cao 2, Qian Tang 1, Haonan Zhao 1

Affiliation(s)

1 Shaanxi University of Traditional Chinese Medicine, Xianyang, Shaanxi, 712000, China
2 Shaanxi Research Institute of Traditional Chinese Medicine, Xi'an, Shaanxi, 710000, China

Corresponding Author

Hui Ding

ABSTRACT

Metabolic syndrome (metabolic syndrome, MS) reaction is systemic metabolic abnormalities, by many types of pathogenic factors together on the human body, blood pressure, blood fat, blood sugar, obesity, disorders, mainly with high uric acid and abnormal coagulation is given priority to, with coronary atherosclerosis, the occurrence of cardiovascular disease. Alanine aminotransferase (ALT) is widely distributed in human body, exists in most tissues and organs, mainly involved in the process of protein digestion and absorption of human body, in which the content of liver cell mitochondria is the highest, so it is used to measure liver function and is also one of the most sensitive indicators reflecting liver damage. Metabolic syndrome is defined as a chronic inflammatory disease, and ALT, as an inflammatory factor associated with metabolic diseases, has a long-term and persistent effect in patients, mainly involved in oxidative stress response, produce a series of immune response effects, leading to damage to hepatocytes, and eventually lead to the level of ALT in the blood of patients. In recent years, there are few relevant studies at home and abroad, but some studies directly confirm that ALT participates in the occurrence and development of MS and plays a certain role in it. Meanwhile, modern medicine suggests that serum ALT levels are also closely related with the MS components. Secondly, ALT can be used to measure and identify MS, so it is expected to be a new predictor of MS. Although there is no clear definition of MS in traditional Chinese medicine, some doctors can attribute the disease location to the liver, spleen and kidney, and the pathogenesis is mainly false and solid, and a large number of studies have found that dampness, heat, phlegm and blood stasis are the main pathological factors, and the clinical treatment is mainly to remove phlegm and remove blood stasis.

KEYWORDS

Metabolic syndrome; ALT; chronic inflammation; oxidative stress; correlation

CITE THIS PAPER

Qi Mao, Hui Ding, Yi Zhou, Jian Cao, Qian Tang, Haonan Zhao, Progress in the relationship between each components of metabolic syndrome and glutamate aminotransferase. MEDS Clinical Medicine (2023) Vol. 4: 6-14. DOI: http://dx.doi.org/10.23977/medsc.2023.040102.

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