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  4. Vol 3, Issue 8, 2022

Probiotics Therapy for the Constipation in Children: An Overview of Systematic Reviews

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DOI: 10.23977/medsc.2022.030803 | Downloads: 7 | Views: 469

Author(s)

Chao Xu 1, Li Liu 1

Affiliation(s)

1 Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 710246, China

Corresponding Author

Chao Xu

ABSTRACT

Objective: To evaluate the methodological bias and the reliability of the conclusions of systematic reviews on constipation. Methods: CNKI, CBM, VIP, WanFang Data, The Cochrane Library, PubMed and EMbase databases were searched to collect systematic reviews or meta-analyses of probiotics therapy for constipation from inception to March, 2022. Two researchers independently screened literature and extracted data. Then, AMSTAR 2 tool and PRISMA statement were used to evaluate the methodological quality and reporting quality of included systematic reviews. Results: A total of 5 systematic reviews were included. The results of AMSTAR 2 suggested that 1 systematic reviews were of extremely low quality, 3 of middle quality, and 1 of high quality. The PRISMA score ranged from 20 to 26. 3 studies were relatively complete, 7 studies had certain defects and one study had serious defects. Conclusions: The existing systematic reviews evidence shows that probiotics may have a certain curative effect in the treatment of constipation in children, but the quality of research methodology, reporting quality and evidence quality still needs to be improved.

KEYWORDS

Constipation, Probiotics, AMSTAR 2, PRISMA, Overview of Systematic Reviews

CITE THIS PAPER

Chao Xu, Li Liu, Probiotics Therapy for the Constipation in Children: An Overview of Systematic Reviews . MEDS Clinical Medicine (2022) Vol. 3: 21-28. DOI: http://dx.doi.org/10.23977/medsc.2022.030803.

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