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Research progress on biomarkers of cerebral small vessel disease

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DOI: 10.23977/medsc.2022.030712 | Downloads: 22 | Views: 564


Chen Ling 1, Longbin Jia 2


1 Changzhi Medical College, Changzhi, Shanxi, 046000, China
2 Department of Neurology, Jincheng People's Hospital, Jincheng, Shanxi, 048000, China

Corresponding Author

Longbin Jia


Relevant data show that with the accelerating aging population in China, cerebral small vessel disease the diagnosis rate of Cerebral small vessel disease (CSVD) is also increasing year by year. Patients may have cognitive decline, gait disorder, mental and emotional changes, swallowing disorder, and abnormal urine and stool, which seriously affect the quality of life. At present, the pathogenesis of CSVD is still unclear. The author believes that the research on biomarkers of CSVD may have broad prospects. Therefore, this paper analyzes the inflammation-related markers of CSVD, Immune-related markers, and genetic-related markers to provide a new reference direction for early diagnosis, disease monitoring, and clinical treatment of CSVD.


Cerebral small vessel disease; Pathogenesis; Biomarkers; Neurofilament Light Chain


Chen Ling, Longbin Jia, Research progress on biomarkers of cerebral small vessel disease. MEDS Clinical Medicine (2022) Vol. 3: 68-74. DOI:


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