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  4. Vol 3, Issue 5, 2022

Comparison of Serum Levels of IL-35, MyD88, hsCRP and NO between Patients with Premature Ventricular Contraction and Healthy Subjects

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DOI: 10.23977/medsc.2022.030517 | Downloads: 5 | Views: 465

Author(s)

Liuyi Li 1, Xiaofang Ren 2, Borui Liu 1, Chunxian Zhao 1, Mengfan Zhao 1, Qingchen Huang 1

Affiliation(s)

1 Shaanxi University of Traditional Chinese Medicine, Xianyang, Shaanxi, 712046, China
2 Xi'an Hospital of Traditional Chinese Medicine Affiliated to Shaanxi University of Chinese Medicine, Xi'an, Shaanxi, 710021, China

Corresponding Author

Xiaofang Ren

ABSTRACT

Objective: To observe the effect of serum levels of IL-35, MyD88, hsCRP and NO in patients with premature ventricular contractions with Qi and Yin deficiency and healthy subjects. Methods: From August 2020 to August 2021, 40 patients with premature ventricular contractions with Qi and Yin deficiency admitted to the outpatient department and inpatient department were divided into the observation group, and 40 healthy people admitted to the treatment center were divided into the control group. The serum levels of IL-35, MyD88, hsCRP and NO in the two groups were observed. Results: The serum levels of IL-35and NO in the observation group were significantly lower than those in the control group, and the differences were statistically significant (P < 0.05). The serum levels of MyD88 and hsCRP in the observation group were significantly higher than those in the control group, and the differences were statistically significant (P < 0.05). Conclusions: Compared with healthy people, the serum levels of MyD88 and hsCRP in patients with QI-Yin deficiency are significantly increased, while the levels of IL-35 and NO are significantly decreased, indicating that there is a relationship between the relevant factors in patients with premature ventricular contraction, which provides experimental theoretical basis for the study of the mechanism of premature ventricular contraction.

KEYWORDS

Premature ventricular contractions, IL-35, MyD88, hsCRP, NO, inflammatory response

CITE THIS PAPER

Liuyi Li, Xiaofang Ren, Borui Liu, Chunxian Zhao, Mengfan Zhao, Qingchen Huang, Comparison of Serum Levels of IL-35, MyD88, hsCRP and NO between Patients with Premature Ventricular Contraction and Healthy Subjects. MEDS Clinical Medicine (2022) Vol. 3: 96-100. DOI: http://dx.doi.org/10.23977/medsc.2022.030517.

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