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Fabrication and Characterization of Paper-Based Microfluidic Devices

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DOI: 10.23977/msom.2022.030204 | Downloads: 8 | Views: 570


Daohong Zhang 1, Xiaoman Guo 1, Jinxin Guo 1


1 Tianjin Key Laboratory of Aquatic Science and Technology, School of Environmental and Municipal Engineering, Tianjin Chengjian University, Tianjin, China

Corresponding Author

Daohong Zhang


Whitesides group published a research paper about paper-based microfluidic devices in 2007. After that, publication about paper-based microfluidic devices increased very fast. Several advantages of those devices made them better choices than traditional dip stick or lateral-flow assays, including inexpensive, biocompatible, easy-fabrication, small size, eco-friendly, etc. Paper-based microfluidic devices were mainly employed in the field of low-cost onsite detection, such as point-of-care detection for disease diagnosis and environmental measurement. Studies about different fabrication methods were also published during these years, which should be considered before utilization of paper-based microfluidic devices. Meanwhile, some aspects, such as materials and chemicals addition may lead to diverse devices performance, which should be carefully chose during device development. We reviewed fabrication methods and parameters characterization of paper-based microfluidic devices in this paper. Hope those information can give researchers interested in paper-based microfluidics a better comparison.


Paper-based microfluidic devices, fabrication, characteristics


Daohong Zhang, Xiaoman Guo, Jinxin Guo, Fabrication and Characterization of Paper-Based Microfluidic Devices. Manufacturing and Service Operations Management (2022) Vol. 3: 24-30. DOI:


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