New Progress in Pharmacochemistry of Anti Enterovirus 71
DOI: 10.23977/medsc.2022.030411 | Downloads: 7 | Views: 112
Honggao Duan 1
1 School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Benxi, Liaoning Province, 117004, PR China
Corresponding AuthorHonggao Duan
Although great progress has been made in the research and development of new drugs against enterovirus 71, the prevention and treatment of enterovirus 71 still relies on vaccines in most cases.Therefore, it is an urgent task to speed up the research and development of anti enterovirus 71 drugs. With the development and integration of multiple disciplines, the research and development directions of anti enterovirus 71 drugs are more diverse.At present, there are further research results on the crystal structure of capsid protein and some key proteases in clinical research. In the future development of anti enterovirus drugs, we can continue to design reasonably on this basis.In this paper, through consulting the relevant literature in recent years, the chemical research of antienterovirus 71 was summarized and analyzed, in order to provide reference for related people.
KEYWORDSEnterovirus 71, Capsid protein inhibitor, Anti virus, Therapeutic drugs
CITE THIS PAPER
Honggao Duan, New Progress in Pharmacochemistry of Anti Enterovirus 71. MEDS Clinical Medicine (2022) Vol. 3: 71-75. DOI: http://dx.doi.org/10.23977/medsc.2022.030411.
 Wang Run. Pharmaceutical care and experience of clinical pharmacists participating in the treatment of a case of methicillin-resistant Staphylococcus aureus infection [J]. Anti infective pharmacy, 2021,18 (10): 1543-1546.
 Zhou Zhenxin, Yi Li, Zhang Han. Correlation between in vitro and in vivo relative potency test of inactivated enterovirus 71 vaccine [J]. Chinese Journal of biologics, 2021,34 (09): 1028-1032.
 Bi Yingjie, Xie Jingying, Li Xie, Feng Ruofei. Research progress in RIG-I-like receptor signaling pathway mediated microRNA virus immune escape [J]. Acta virologica Sinica, 2021,37 (04): 1004-1010.
 Wang Wenqi, Li Yuanyuan, Wang Shuang. Study on antiviral active components of total flavonoids from Patrinia villosa [J]. Shandong science, 2020, 33 (05): 43-50
 An Yunxia. Efficacy analysis of recombinant human basic fibroblast growth factor combined with open throat sword in the treatment of herpangina [J]. Chinese Journal of modern medicine, 2020, 22 (07): 48-50.
 Lu Chuanbin. Children in spring and summer should guard against enterovirus invasion [J]. New countryside, 2016, (05): 44.
 Dong, Zhang and Hu. Research technology and application status of virus cell receptor [J]. Chinese Journal of veterinary medicine, 2016,50 (02): 63-66.
 Li Duoyun, Liu Xiaojun, Cheng hang. Experimental study on the regulation and expression of enterovirus 71 VP1 protein by Bifidobacterium in intestine [J]. Chinese Journal of pathogenic biology, 2014,9 (05): 422-426 + 465.
 Qi Xiangyun, Li Kang, Xia Yanping. The proliferation kinetics of enterovirus 71 in RD cells and Vero cells [J]. Biotechnology communication, 2014,25 (03): 333-336.
 Xia Xuelong, Li Haihua. Effect of gamma globulin on cytokines in children with severe EV71 infection [J]. Journal of medical research, 2013,42 (06): 111-115.
 Gao Yali, Ni Xin, Ma Junjie. Synthesis of a novel small molecule vascular endothelial growth factor receptor inhibitor furquitinib [J]. Chinese Modern Applied Pharmacy, 2020,37 (24), 2962-2965.
 Wu Zimei, Li Linyu, Chen Lu. Research progress of programmed cell death receptor-1 / programmed cell death receptor ligand-1 inhibitors in the treatment of colorectal cancer [J]. Shanghai pharmaceutical, 2020, 41 (15): 49-51.
 Liu Zhiqiang. Molecular docking of major flavonoids in Huangqin Shegan Decoction with neuraminidase of h7n9 virus [J]. Journal of Shaoyang University: Natural Science Edition, 2020, 17 (3): 76-78.
 Ruan Lixin, Chen Huirui. Clinical efficacy of Lactobacillus reuteri adjuvant treatment in children with rotavirus enteritis and its influence on intestinal flora [J]. Jiangxi Medical Journal, 2021, 56 (12): 38-40.
 Kang Ping, sun Xiaomin, Zhao Shaocong. The significance of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in the progression of respiratory syncytial virus bronchiolitis to asthma [J]. Journal of practical medicine, 2020,12 (25) 38-41.