Analysis of high-risk HPV infection and cervical HPV in 10670 women
DOI: 10.23977/medsc.2022.030314 | Downloads: 5 | Views: 686
Author(s)
Tao Bai 1, Ynchun Qian 1, Yao Yuan 1, Jing Cai 2
Affiliation(s)
1 Shaanxi University of Traditional Chinese Medicine, Xianyang, 71200, Shaanxi, China
2 Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine, Xianyang, 71200, Shaanxi, China
Corresponding Author
Jing CaiABSTRACT
Objective To analyze the infection of cervical high-risk HPV (HR-HPV), study the correlation of cervical HR-HPV infection and help the clinical cervical cancer screening. Methods Statistics from January 2019 to December 2020 in the gynecological outpatient department of 10670 women of cervical HPV infection, among which 731 patients with cervical HR-HPV infection underwent colposcopy + cervical biopsy, analyzed the relationship between cervical HR-HPV infection and cervical pathology results, clear the association between cervical HR-HPV infection and cervical lesions. Results 10670 female HR-HPV patients, with the highest number of 20.00% (347/1738), and the top 5 single infections were 16,52,58,53 and 51.HR-HPV infected patients were divided into four categories according to type 16,18, other 13 and multiple infections, and the other 13 types accounted for the most proportion, with 59.09% (1027/1738).The 347 patients with multiple infection had the highest rate of other type 13 coinfection, accounting for 60.23% (209/347).A total of 1738 patients with HR-HPV infection were divided into five groups according to their age, and the number of women aged 41 to 50 was the largest (29.34%), second by> 50 years (28.48%), with HPV16 and 18 infections mainly from 41 to 50 and> 50 years, as were other 13 high-risk HPV infections.HR-HPV infection at different ages was statistically significant (c2=61.419, P=0.000<0.05).In 731 patients with HR-HPV infection undergoing cervical biopsy in our hospital, pathological cervical low-grade intraepithelial lesions were mainly other type 13 infections, accounting for 58.17% (356/612); cervical high-grade intraepithelial lesions were mainly type 16 infections (including single type 16,16 and other type 13 infections), accounting for 67.23% (80/119).The distribution of HR-HPV type in the pathological diagnosis of cervical biopsy was statistically significant (c2=126.830, P=0.000<0.05).Conclusion HR-HPV infection can increase the incidence of cervical precancerous lesions and cervical cancer is mainly type HPV16.
KEYWORDS
High-risk HPV (HR-HPV), cervical lesionsCITE THIS PAPER
Tao Bai, Ynchun Qian, Yao Yuan, Jing Cai, Analysis of high-risk HPV infection and cervical HPV in 10670 women. MEDS Clinical Medicine (2022) Vol. 3: 81-89. DOI: http://dx.doi.org/10.23977/medsc.2022.030314.
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