Author(s)

Gao Yiming ¹

Affiliation(s)

¹ School of Life Sciences, Fudan University, Shanghai 200433, China

Corresponding Author

Gao Yiming

ABSTRACT

As a new strategy to prevent and treat depression, exercise has a good therapeutic effect on depressive symptoms associated with major diseases such as cardiovascular and cerebrovascular diseases and tumors; However, whether exercise can be used as an independent factor in the prevention and treatment of depression still lacks sufficient theoretical basis. Based on neural plasticity and the neurobiological changes related to neurons and glial cells, this topic will explore the occurrence of depression and the antidepressant effect of exercise from multiple angles and levels, so as to provide a more reliable theoretical basis for exercise as an independent factor in the prevention and treatment of depression.

KEYWORDS

Exercise, Antidepressant nerve, Biological mechanism

CITE THIS PAPER

Gao Yiming, Study on Neurobiological Mechanism of Exercise Antidepressant. MEDS Clinical Medicine (2022) Vol. 3: 76-80. DOI: http://dx.doi.org/10.23977/medsc.2022.030313.

REFERENCES

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[4] SITENESKI, ALINE, OLESCOWICZ, GISLAINE, PAZINI, FRANCIS L., et al. Antidepressant-like and pro-neurogenic effects of physical exercise: the putative role of FNDC5/irisin pathway[J]. Journal of neural transmission,2020,127(3):355-370.
[5] RADMARK, L., HANSON, L. L. MAGNUSSON, MONTGOMERY, S., et al. Mind and body exercises (MBE), prescribed antidepressant medication, physical exercise and depressive symptoms - a longitudinal study[J]. Journal of affective disorders,2020,265, 185-192.
[6] RODRIGUES, R., MOREIRA, J. B., SEBASTIAO, A. M., et al. From cannabinoids to physical exercise: regulators of postnatal neurogenesis as antidepressant targets?[J]. European neuropsychopharmacology: the journal of the European College of Neuropsychopharmacology,2020,31, S1-S2.

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