Author(s)

Fu Fangzhi ^1,2, Yin Shuang ², Zhou Qing ¹

Affiliation(s)

¹ The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha 410007, China
² Hunan University of Chinese Medicine, Changsha 410208, China

Corresponding Author

Zhou Qing

ABSTRACT

Objective: To systematically evaluate the efficacy and safety of Xiaochaihu decoction in the treatment of gastroesophageal reflux disease (GERD). Methods: The databases of CNKI, VIP, WanFang, PubMed and the Cochrane Library were searched to find out the clinical studies of Xiaochaihu decoction in the treatment of gastroesophageal reflux disease and conduct a meta-analysis. And the time limit was from the establishment of the database to September 2021. Results: A total of 10 studies with a total of 1173 patients were included. Meta-analysis results showed that, compared with conventional western medicine, Xiaochaihu decoction can significantly improve the clinical cure rate, gastroscopy cure rate, clinical total effective rate and total gastroscopy total effective rate of GERD, and reduce the recurrence rate and rate of adverse reactions. Conclusion: Xiaochaihu decoction has superior efficacy and safety in the treatment of GERD. 

KEYWORDS

Xiaochaihu decoction, conventional western medicine, gastroesophageal reflux disease, meta-analysis

CITE THIS PAPER

Fu Fangzhi, Yin Shuang, Zhou Qing, Meta-analysis of Xiaochaihu Decoction in the Treatment of Gastroesophageal Reflux Disease. MEDS Clinical Medicine (2022) Vol. 3: 72-75. DOI: http://dx.doi.org/10.23977/medsc.2022.030312.

REFERENCES

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