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Effects of Xuanhuang ointment on histomorphology and appearance of acute soft tissue injury in rats

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DOI: 10.23977/phpm.2022.020208 | Downloads: 2 | Views: 117

Author(s)

Mingming Wang 1, Yan Cheng 2

Affiliation(s)

1 Shaanxi University of Traditional Chinese Medicine, Xian Yang 712046, China
2 Shaanxi Hospital of Traditional Chinese Medicine, Xi'an 710003, China

Corresponding Author

Yan Cheng

ABSTRACT

Objective: To observe the effect of Xuanhuang ointment on the morphology and appearance of local soft tissue in rats with acute soft tissue injury. Methods: The acute soft tissue injury model of rats was established and randomly divided into Xuanhuang ointment group, safflower oil group and matrix ointment group. Another 5 rats were taken as the normal group. In addition to the normal group, apply ointment on the injured part of the right lower limb thigh, cover the injured tissue, and then wrap it with breathable film, medical tape and bandage. Change the dressing once every other day, three times in total. On the 3rd, 5th and 7th day of the experiment, the visual observation of the surface damage degree of local soft tissue in each group was compared; On the 1st, 3rd, 5th and 7th day after treatment, the local soft tissue was taken and the histomorphological changes were observed under light microscope. On the 7th day of the experiment, the histopathology of rats in each group was statistically compared. Results: The blood stasis at the injured part in Xuanhuang ointment group and safflower oil group disappeared significantly, and the repair of muscle fibers was faster than that in matrix ointment group. Conclusion Xuanhuang ointment has the effects of anti inflammation and detumescence, promoting blood circulation and removing blood stasis, and can accelerate the repair of muscle fibers.

KEYWORDS

Acute soft tissue injury, Xuanhuang ointment, Histomorphology

CITE THIS PAPER

Mingming Wang, Yan Cheng, Effects of Xuanhuang ointment on histomorphology and appearance of acute soft tissue injury in rats. MEDS Public Health and Preventive Medicine (2022) Vol. 2: 47-52. DOI: http://dx.doi.org/10.23977/phpm.2022.020208.

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