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Research Progress of Tumor Cell Vaccine

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DOI: 10.23977/medcm.2021.030207 | Downloads: 7 | Views: 775

Author(s)

Nannan Zhang 1, Qing Zhang 1, Yanan Sun 1, Ruiying Hu 1, Lingru Chen 1, Zhenqiu Gao 1

Affiliation(s)

1 School of Pharmacy, Yancheng Teachers University, Xiwang Road, Yancheng 224007, China

Corresponding Author

Zhenqiu Gao

ABSTRACT

With the rapid development of biotechnology in recent years, the research of tumor vaccine has made gratifying progress. In recent years, the research of tumor cell vaccine has been paid more and more attention. In 1893, Coley used the bacterial extract of Dandu patients to stimulate tumor specific immune response and treat malignant tumor. Subsequently, Corynebacterium and BCG were widely used as Immunoenhancers in clinical. In the 1950s, people began to study autogenous tumor vaccine. Therefore, active immunotherapy (tumor vaccine) is the fourth effective tumor treatment method after surgery, radiotherapy and chemotherapy. As active and specific immunotherapy, tumor vaccine plays an increasingly important role in clinical treatment. This paper reviews the introduction, research history, mechanism, challenges and prospects of tumor cell vaccine.

KEYWORDS

Tumor cell vaccine, Progress, Clinical effect, Tumor immune escape, Adverse reactions

CITE THIS PAPER

Nannan Zhang, Qing Zhang, Yanan Sun, Ruiying Hu, Lingru Chen, Zhenqiu Gao. Research Progress of Tumor Cell Vaccine. MEDS Chinese Medicine (2021) 3: 25-28. DOI: http://dx.doi.org/10.23977/medcm.2021.030207.

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