Author(s)

Li Zirui ^1,2, Ma Min ^1,2, Ran Maoxing ¹, Liu Yuanjun ^1,2, Wu Xiaoling ³, Dang Huimin ²

Affiliation(s)

¹ Shaanxi University of Chinese Medicine, Xianyang, China
² Department of Traditional Chinese Medicine, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China
³ Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China

Corresponding Author

Dang Huimin

ABSTRACT

High-risk human papillomavirus (HPV) infection is a major cause of cervical cancer, while current prevention and treatment strategies remain limited. Traditional Chinese Medicine (TCM) has shown unique advantages in the prevention and treatment of HPV infection. According to TCM theory, its core pathogenesis is characterized by deficiency of healthy qi as the root and dampness, heat, and toxin as the manifestations, and it is often categorized as "leukorrheal diseases" or "abdominal masses." Therapeutic strategies include both internal and external administration, following the principles of strengthening healthy qi, eliminating pathogens, clearing heat and dampness, promoting blood circulation, and removing toxins. A growing number of clinical studies have demonstrated that TCM can effectively promote HPV clearance, relieve clinical symptoms, regulate immune function, and improve the vaginal microenvironment, with a favorable safety profile. In the future, greater efforts should be made to establish unified efficacy evaluation criteria, optimize TCM formulations, and strengthen evidence-based research, so as to promote its broader clinical application.

KEYWORDS

Human Papillomavirus, Traditional Chinese Medicine, Pathogenesis, Syndrome Differentiation and Treatment, Immunomodulation

CITE THIS PAPER

Li Zirui, Ma Min, Ran Maoxing, Liu Yuanjun, Wu Xiaoling, Dang Huimin. Traditional Chinese Medicine in the Treatment of HPV Infection: A Review. MEDS Chinese Medicine (2026). Vol. 8, No. 1, 78-90. DOI: http://dx.doi.org/10.23977/medcm.2026.080110.

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