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Mechanism of action and research progress of Banxia Xiexin Tang in the treatment of gastric cancer

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DOI: 10.23977/medcm.2025.070303 | Downloads: 7 | Views: 775

Author(s)

Congcong Yu 1, Ao Xu 1, Ruobing Yao 1, Zhonghua Xie 1, Jiao Tian 1, Keqiong Wang 1,2

Affiliation(s)

1 Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China
2 The First Clinical Medical College of Shaanxi University of Chinese Medicine, The Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xi’an, Shaanxi, 712046, China

Corresponding Author

Keqiong Wang

ABSTRACT

Half-summer diarrhea heart soup is a classic formula in the Treatise on Typhoid Miscellaneous Diseases. It has been used for treating a variety of spleen and stomach disorders based on the symptoms of plumpness under the heart and the mixture of cold and heat. Recent studies have found that this formula has multi-target effects in regulating gastrointestinal function, anti-inflammatory, anti-tumor and metabolic diseases. In this paper, we will systematically describe its chemical composition, pharmacological mechanism and clinical research progress in the treatment of gastric cancer, so as to provide more scientific and accurate data support for future clinical application. With the development of modern society and the improvement of economic level, people's living habits have undergone significant changes, and the occurrence of diseases has followed. gastric cancer (GC) is one of the tumors with high prevalence in the world, and the survival rate of patients within 5 years is only about 20%[1] .The number of incidence and death of gastric cancer in China is the highest in the world, accounting for about 43.9% and 48.6%[2].The emergence of new treatment modalities such as immunization and targeted therapy has improved the prognosis of patients to some extent. In Chinese medicine, cancer is referred to as the accumulation of obstruction in the abdomen, which has been recorded by the ancients. With the development of modern science and technology, the mechanism of action of Banxia Xiexin Tangin treating gastric cancer has been gradually clarified, and this paper aims to summarize the mechanism of action and research progress of hemixia laxative heart soup.

KEYWORDS

Banxia Xiexin Tang, Typhoid Miscellaneous Diseases Treatise, gastric cancer, mechanism of action

CITE THIS PAPER

Congcong Yu, Ao Xu, Ruobing Yao, Zhonghua Xie, Jiao Tian, Keqiong Wang, Mechanism of action and research progress of Banxia Xiexin Tang in the treatment of gastric cancer. MEDS Chinese Medicine (2025) Vol. 7: 15-20. DOI: http://dx.doi.org/10.23977/medcm.2025.070303.

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