Author(s)

Ye Xiaolei ^1,2, Li Shimei ², Wang Suli ², Zhang Caiqing ²

Affiliation(s)

¹ Shaanxi University of Traditional Chinese Medicine, Xianyang, 712046, China
² 986th Hospital of Plaaf, Xi'an, 710054, China

Corresponding Author

Zhang Caiqing

ABSTRACT

The objective of the paper is to use the Chinese medicine inheritance auxiliary platform (V2.5) to explore the rules of medication used by Professor Yang Jialin, a national famous veteran Chinese medicine practitioner, in the treatment of menstrual disorders. The method applied in this paper is to read and collect the prescriptions of 'China's Modern Hundred Chinese Medicine Clinicians-Yang Jialin' for the treatment of menstrual diseases, to establish a database of prescriptions by using the Chinese Medicine Inheritance Auxiliary Platform (V2.5), and to carry out the statistics and analysis of the data by frequency counting analysis, correlation rules, and clustering analysis. A total of 18 formulas were selected from the book, 71 flavours of drugs were used, and the total number of times they were used was 206. The top ten most frequently used drugs were, in descending order, white peony, angelica sinensis, wolfberry, ligusticum chuanxiong, chickweed vine, cuscuta, chaihu, ripened diclofenac, motherwort, and cimicifuga; the drug meridians were liver meridian, followed by spleen and kidney meridians; the four qi of the drug were cold and warm, followed by flatness; and the flavours of the drug were sweet and bitter, followed by pungent and acidic flavours. Twenty-three drug combinations were obtained by association rule analysis; six core drug groups and three new prescriptions were obtained by cluster analysis. The conclusion of this thesis is that the academic characteristics of Professor Yang Jialin's treatment of menstrual disorders are: emphasis on the liver, spleen and kidneys, and treatment according to different age groups; classification of menstrual disorders as either too much or too little, and either passage or regulation according to the menstrual cycle; and the use of medication based on the Four Substance Soup, with a great deal of emphasis on qi and blood.

KEYWORDS

Menstrual disorders; medication patterns; data mining; Yang Jialin

CITE THIS PAPER

Ye Xiaolei, Li Shimei, Wang Suli, Zhang Caiqing. Exploring the pattern of identification and use of drugs in the treatment of menstrual disorders by Yang Jialin based on data mining. MEDS Clinical Medicine (2024) Vol. 5: 137-144. DOI: http://dx.doi.org/10.23977/medsc.2024.050519.

REFERENCES

[1] Zeng Qian, Li Ruowei, Wei Shiyin, et al. Reading Classics to Interpret Professor Yang Jialin's Theory of Reproductive Axis[J]. World Science and Technology-Modernisation of Traditional Chinese Medicine, 2015, 17(12):2543-2546.
[2] Yang Jialin. Yang Jialin [M]. Beijing: China Traditional Chinese Medicine Press, 2009. 11.
[3] Li J, Shi JF, Nie X, et al. Research on the mechanism of action of Siwu Tang for primary dysmenorrhoea based on network pharmacology [J]. Chinese Journal of Traditional Chinese Medicine, 2019, 44(03):559-565.
[4] Zhu Min, Duan Jin Gran, Tang Yu Ping, et al. Effects of Siwu Tang and its group formulae of drug pairs and flavours on primary dysmenorrhoea model in mice [J]. Chinese Journal of Experimental Formulas, 2010, 16(18):109112.
[5] Cui Lixia, Shi Danning, Jiao Shihong, et al. Effects of Sizutang on the proliferation of MC3T3-E1 cells based on G protein-coupled estrogen receptor-mediated EGFR/PI3K pathway[J]. Journal of Beijing University of Chinese Medicine, 2019, 42(11):923-933.

Sponsors, Associates, and Links

---

• Journal of Neurobiology and Genetics
  
  
• Medical Imaging and Nuclear Medicine
  
  
• Bacterial Genetics and Ecology
  
  
• Transactions on Cancer
  
  
• Journal of Biophysics and Ecology
  
  
• Journal of Animal Science and Veterinary
  
  
• Academic Journal of Biochemistry and Molecular Biology
  
  
• Transactions on Cell and Developmental Biology
  
  
• Rehabilitation Engineering & Assistive Technology
  
  
• Orthopaedics and Sports Medicine
  
  
• Hematology and Stem Cell
  
  
• Journal of Intelligent Informatics and Biomedical Engineering
  
  
• MEDS Basic Medicine
  
  
• MEDS Stomatology
  
  
• MEDS Public Health and Preventive Medicine
  
  
• MEDS Chinese Medicine
  
  
• Journal of Enzyme Engineering
  
  
• Advances in Industrial Pharmacy and Pharmaceutical Sciences
  
  
• Bacteriology and Microbiology
  
  
• Advances in Physiology and Pathophysiology
  
  
• Journal of Vision and Ophthalmology
  
  
• Frontiers of Obstetrics and Gynecology
  
  
• Digestive Disease and Diabetes
  
  
• Advances in Immunology and Vaccines
  
  
• Nanomedicine and Drug Delivery
  
  
• Cardiology and Vascular System
  
  
• Pediatrics and Child Health
  
  
• Journal of Reproductive Medicine and Contraception
  
  
• Journal of Respiratory and Lung Disease
  
  
• Journal of Bioinformatics and Biomedicine