Author(s)

Xiaoxiao Wan ¹, Ping Zhou ¹

Affiliation(s)

¹ Department of Nephrology, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, Jiangxi, 330006, China

Corresponding Author

Xiaoxiao Wan

ABSTRACT

This study investigates the impact of blood pressure variability (BPV) on early failure and patency outcomes of arteriovenous fistulas (AVFs) in patients with end-stage renal disease (ESRD). Short-term and long-term BPV parameters, including standard deviation of systolic blood pressure (SBP-SD), blood pressure variability coefficient (BCV), and average real variability (ARV), were analyzed in 100 patients who underwent AVF surgery between 2019 and 2023. The results indicate that high BPV significantly increases the risk of early AVF failure (hazard ratio [HR] = 1.48, 95% confidence interval [CI]: 1.23-1.75, P < 0.01). Kaplan-Meier analysis revealed a significantly higher rate of patency failure in patients with persistently high BPV (Log-rank P < 0.01). The influence of BPV on AVF function is independent of traditional risk factors, suggesting that clinical monitoring and control of BPV can help improve AVF prognosis. Future research is needed to validate its predictive value through larger sample sizes and longer follow-up periods.

KEYWORDS

Blood Pressure Variability (BPV), Arteriovenous Fistula (AVF), End-Stage Renal Disease (ESRD), Early Failure, Revascularization Outcome

CITE THIS PAPER

Xiaoxiao Wan, Ping Zhou. Study on the Correlation between Blood Pressure Variability and Early Arteriovenous Fistula Failure and Recanalization in End-Stage Renal Disease. MEDS Clinical Medicine (2024) Vol. 5: 88-97. DOI: http://dx.doi.org/10.23977/medsc.2024.050513.

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