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  4. Vol 5, Issue 5, 2024

Research Progress of Stem Cells from Human Exfoliated Deciduous Teeth (SHED) and Dental Pulp Stem Cells (DPSCs)

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DOI: 10.23977/medsc.2024.050501 | Downloads: 18 | Views: 366

Author(s)

Bai Jiayi 1, Li Ziwei 1, Min Yangtan 1, Zhao Yaning 2

Affiliation(s)

1 Xi'an Jiaotong University, Xi'an City, Shaanxi Province, China
2 The Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang City, Shaanxi Province, China

Corresponding Author

Zhao Yaning

ABSTRACT

Stem cells from human exfoliated deciduous teeth (SHED) and dental pulp stem cells (DPSCs) exhibit significant potential in regenerative medicine, particularly in areas such as tooth repair, neural regeneration, and bone tissue repair. This paper reviews the latest research progress of these two types of cells in terms of their origins and isolation, proliferation and differentiation abilities, and immunomodulatory properties, providing a detailed analysis of their applications in tissue repair. By comparing the similarities and differences between SHED and DPSCs, we identify the unique advantages and challenges of each in terms of biological characteristics and applications. This paper further explores the technological bottlenecks in current research and the feasibility of clinical translation, and provides an outlook on future research directions to offer theoretical support for advancing related scientific research.

KEYWORDS

Stem cells from human exfoliated deciduous teeth; Dental pulp stem cells; Regenerative medicine; Tissue repair

CITE THIS PAPER

Bai Jiayi, Li Ziwei, Min Yangtan, Zhao Yaning. Research Progress of Stem Cells from Human Exfoliated Deciduous Teeth (SHED) and Dental Pulp Stem Cells (DPSCs). MEDS Clinical Medicine (2024) Vol. 5: 1-8. DOI: http://dx.doi.org/10.23977/medsc.2024.050501.

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