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  4. Vol 5, Issue 4, 2024

Diagnostic Efficacy of Hypersensitive C-reactive Protein and Blood Routine Test in Different Respiratory Pathogen Infections in Children

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DOI: 10.23977/medsc.2024.050415 | Downloads: 20 | Views: 720

Author(s)

Yingxi Li 1, Liang Ming 1, Zhaofan Luo 1

Affiliation(s)

1 Department of Clinical Laboratory, The Seventh Affiliated Hospital of Sun Yat-sen University, Shenzhen, Guangdong, 518107, China

Corresponding Author

Zhaofan Luo

ABSTRACT

To investigate the value of hypersensitive C-reactive protein (hs-CRP) and blood routine test in the diagnosis of different respiratory pathogen infections in children, we selected children with respiratory pathogen infections received from November 2023 to January 2024 as the observation group. And 137 children who were admitted to the hospital for treatment but not with respiratory pathogen infections during the same period were selected as the control group, with the children in the observation group classified into 128 cases of mycoplasma pneumoniae, 57 cases of influenza A and B viruses, and 240 cases of adenovirus according to the types of different pathogen infections. Blood indicators were collected from the study subjects to detect the hs-CRP level with the Mindray CRP-M100, detect the levels of white blood cell count (WBC), neutrophil percentage (NEUT%), lymphocyte percentage (LY%), monocyte percentage (MO%), percentage of eosinophilic cells (EO%), and percentage of basophilic cells (BASO%) with a hematology analyzer. The detected results of indicators in each group and detection methods were compared to detect the positive results. The blood hs-CRP levels of the mycoplasma pneumoniae group, the influenza A and B viruses group, and the adenovirus group were all higher than those of the control group (P < 0.05), with the hs-CRP detection value of the influenza A and B viruses group being the highest, followed by the mycoplasma pneumoniae group and the adenovirus group. The differences in the detection indicators of different pathogens were statistically significant in the comparison (P < 0.05). The levels of WBC, NEUT% and MO% in the detection of each pathogen infection group were higher than those in the control group, and the levels of LY% and EO% were both lower than those in the control group (P < 0.05), and the WBC level in the adenovirus group was higher than that in the other 3 groups (P < 0.05). The positive detection rate of different pathogens by hs-CRP+blood routine test was higher than that of single hs-CRP test or single blood routine test (P<0.05). For respiratory pathogen infections in children, hs-CRP and routine blood tests are valuable in determining the type of disease, with the combination of tests increasing the positive detection rate, which is worthy of popularization.

KEYWORDS

Respiratory pathogen infection; Children; Hypersensitive C-reactive protein; Blood routine test; Diagnosis

CITE THIS PAPER

Yingxi Li, Liang Ming, Zhaofan Luo, Diagnostic Efficacy of Hypersensitive C-reactive Protein and Blood Routine Test in Different Respiratory Pathogen Infections in Children. MEDS Clinical Medicine (2024) Vol. 5: 111-117. DOI: http://dx.doi.org/10.23977/medsc.2024.050415.

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