Author(s)

Guangbo Zhang ¹

Affiliation(s)

¹ Occupational Diseases Hospital of Shandong First Medical University, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China

Corresponding Author

Guangbo Zhang

ABSTRACT

Chronic obstructive pulmonary disease (COPD) seriously affects patients' health and daily life. Its coexistence with silicosis leads to an extremely critical clinical situation and serious death. In this article, a randomized controlled trial design was used to evaluate the clinical efficacy of salt rock aerosol in the treatment of COPD and silicosis. The treatment group received salt aerosol treatment, while the control group received routine treatment. The assessment mainly involved lung function, quality of life and inflammatory markers. The lung function, St. George's Breathing Questionnaire (SGRQ) score and high-sensitivity C-reactive protein level were evaluated in all patients. The results showed that the salt rock aerosol treatment effectively improved the forced vital capacity (FVC) of COPD patients with silicosis. The maximum FVC values of the treatment group and the control group were 2.99 liters and 2.47 liters respectively. In addition, the average total score of SGRQ decreased significantly in the treatment group, indicating that the quality of life was improved. The level of inflammatory marker C-reactive protein was also low in the treatment group, and the level did not exceed 6.4mg/L in any treatment group, but reached 14.7mg/L in the control group, which proved the anti-inflammatory effect of salt rock aerosol therapy.

KEYWORDS

Chronic Obstructive Pulmonary Disease; Salt Rock Aerosol Therapy; Forced Lung Capacity; C-reactive Protein

CITE THIS PAPER

Guangbo Zhang, Clinical Efficacy Evaluation of Salt Rock Aerosol Therapy in Patients with Chronic Obstructive Pulmonary Disease Complicated with Silicosis. MEDS Clinical Medicine (2024) Vol. 5: 145-153. DOI: http://dx.doi.org/10.23977/medsc.2024.050322.

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