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  4. Vol 6, Issue 2, 2024

Advances in Traditional Chinese and Western Medicine Research on Diabetic Peripheral Neuropathy

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DOI: 10.23977/medcm.2024.060215 | Downloads: 1 | Views: 43

Author(s)

Xiayixing Wang 1, Ruixia Pei 2

Affiliation(s)

1 Shaanxi University of Chinese Medicine, Xianyang, China
2 Xi'an Hospital of Traditional Chinese Medicine, Xi'an, China

Corresponding Author

Ruixia Pei

ABSTRACT

Diabetic Peripheral Neuropathy (DPN) is a common chronic complication of diabetes, and its incidence and disability rates rising annually. Its symptoms are variable, and its course is lingering, and it is difficult to cure, ultimately leading to disability in diabetes mellitus (DM) patients, which has a huge impact on their physical and psychological well-being, increasing their economic burden. Traditional Chinese Medicine (TCM) attributes DPN to deficiencies in visceral yin-yang and qi-blood, along with blood stasis and blockage. Western medicine identifies dyslipidemia, oxidative stress (OS), autoimmunity, gut microbiota imbalance, and impaired insulin-mediated PI3K/protein kinase B (AKT) signaling pathways as causes of DPN. Western medicine does not have clear specific drugs, and mostly focuses on the etiology, symptomatic treatment, and surgical treatments. TCM employs various methods, including herbal treatments and acupuncture, to improve clinical symptoms from multiple perspectives. This article synthesizes DPN pathogenesis and treatment approaches from both TCM and modern medical perspectives, aiming to provide new insights for DPN treatment.

KEYWORDS

Diabetes peripheral neuropathy; Traditional Chinese and Western medicine; Research progress

CITE THIS PAPER

Xiayixing Wang, Ruixia Pei, Advances in Traditional Chinese and Western Medicine Research on Diabetic Peripheral Neuropathy. MEDS Chinese Medicine (2024) Vol. 6: 117-126. DOI: http://dx.doi.org/10.23977/medcm.2024.060215.

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