Author(s)

Mengni Ren ¹

Affiliation(s)

¹ The Third People's Hospital of Hangzhou, Hangzhou, China

Corresponding Author

Mengni Ren

ABSTRACT

To explore the clinical characteristics and nursing strategies of patients with severe drug eruption. A total of 50 patients with severe drug eruption diagnosed in our hospital from 2020 to 2024 were selected. The clinical characteristics and nursing effects of patients with severe drug eruption were studied through medical records, laboratory examinations and comprehensive nursing intervention. Among the 50 patients, 38 (76.00%) were male and 12 (24.00%) were female. The age of onset ranged from 9 months to 84 years, with an average of (46.31 ± 23.22) years. The body weight ranged from 11 to 100(59.03 ±17.85) kg. Seven patients (14.00%) had a history of drug allergy. The age of onset was mostly between 20 and 60 years old, and most of them were male. The most common clinical manifestation of severe drug eruption was mucosal involvement, followed by fever and pruritus. The most common type with mucosal involvement was SJS, followed by TEN, and the least common type with mucosal involvement was AGEP. The most common type of fever was AGEP. The most common symptom associated with pruritus was TEN. After clinical comprehensive nursing intervention, there were 37 effective patients (74.00%) and only 2 ineffective patients (4.00%), and the treatment effect was good. Severe drug eruption can happen at any age, the incubation period, the clinical symptoms except desquamation, bulla and many parts of mucosal involvement, also may be accompanied by high fever, viscera function damage, etc., come on urgent, case fatality rate is high, once has the symptoms, should be timely withdrawal, positive system integrated nursing treatment, effectively relieve symptoms, promote disease recovery.

KEYWORDS

Severe drug eruption; Clinical characteristics; Nursing effect

CITE THIS PAPER

Mengni Ren, Patients with severe drug eruption analysis of clinical characteristics and nursing effect. MEDS Public Health and Preventive Medicine (2024) Vol. 4: 33-38. DOI: http://dx.doi.org/10.23977/phpm.2024.040205.

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