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Analysis of the effect of sodium valproate on neuroimmune response in patients with refractory epilepsy

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DOI: 10.23977/medsc.2024.050310 | Downloads: 0 | Views: 91

Author(s)

Yanyan Zhang 1, Tianqian Jia 1, Xiaojuan Li 1, Yueyan Wang 1

Affiliation(s)

1 School of Medical Engineering, Haojing College of Shaanxi University of Science & Technology, Xi'an, Shaanxi, 712000, China

Corresponding Author

Yanyan Zhang

ABSTRACT

Epilepsy belongs to a typical group of chronic nervous system diseases, which is characterized by abnormal neuronal discharge. Patients with refractory epilepsy have poor response to traditional antiepileptic drugs. It is of great significance to select an effective regimen for the treatment of patients. Sodium valproate (VPA) is widely used as a first-line AED in the treatment of epilepsy, and the application of this drug is of great significance for the treatment of patients with epilepsy. This article is divided into four aspects to describe in detail the effects of sodium valproate on neuroimmune response in patients with refractory epilepsy. Firstly, the pharmacological effect of sodium valproate is analyzed, then the research progress of sodium valproate combined with other drugs in the treatment of refractory epilepsy is discussed, the specific effect of sodium valproate on neuroimmune response in patients with refractory epilepsy is discussed, and the research situation of this topic is prospected. It is hoped that this paper can provide reference materials for the research work of relevant personnel.

KEYWORDS

Sodium valproate; Patients with refractory epilepsy; Neuroimmune response

CITE THIS PAPER

Yanyan Zhang, Tianqian Jia, Xiaojuan Li, Yueyan Wang, Analysis of the effect of sodium valproate on neuroimmune response in patients with refractory epilepsy. MEDS Clinical Medicine (2024) Vol. 5: 63-67. DOI: http://dx.doi.org/10.23977/medsc.2024.050310.

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