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Performance of the Dengue NS1 Rapid Test in Detecting Dengue Virus Infection: A Comprehensive Study

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DOI: 10.23977/medsc.2024.050307 | Downloads: 4 | Views: 124

Author(s)

Lei Zhang 1, Feng Yang 2, Junzhe Zhu 3

Affiliation(s)

1 Zhejiang Gongshang University, Hangzhou, Zhejiang, 310018, China
2 Community Health Service Center, Yipeng Street, Qiantang District, Hangzhou, Zhejiang, 310000, China
3 Wenzhou Medical University, Wenzhou, Zhejiang, 310000, China

Corresponding Author

Lei Zhang

ABSTRACT

Dengue virus infection presents a substantial global health challenge, impacting millions of individuals worldwide. It manifests in various forms including dengue fever, dengue hemorrhagic fever and dengue shock syndrome. The objective of this study was to assess the diagnostic accuracy of the Dengue NS1 Rapid Test, which is crucial for effective management and prevention of dengue virus infection progression. To assess the sensitivity, specificity and accuracy of the Dengue NS1 Rapid Test, we conducted a comprehensive analysis of 351 specimens. The evaluation showed an accuracy of 96.0%, coupled with a sensitivity of 95.8% and a specificity of 96.1%. The test's specificity was confirmed through cross-reactivity assessments, as it yielded negative results for various other viral strains. Developed by Hangzhou AllTest Biotech Co., Ltd, the Dengue NS1 Rapid Test provides rapid and reliable results, demonstrating a high level of accuracy. As a result, it serves as a valuable diagnostic tool in clinical scenarios, especially in environments with limited resources. The early detection capabilities of this test enable timely interventions, improving the management of dengue virus infections. This leads to better results for patients and a lower rate of virus transmission.

KEYWORDS

Dengue virus, NS1, rapid test, diagnostics

CITE THIS PAPER

Lei Zhang, Feng Yang, Junzhe Zhu, Performance of the Dengue NS1 Rapid Test in Detecting Dengue Virus Infection: A Comprehensive Study. MEDS Clinical Medicine (2024) Vol. 5: 45-49. DOI: http://dx.doi.org/10.23977/medsc.2024.050307.

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