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  4. Vol 5, Issue 3, 2024

Research Progress on Omeprazole in the Treatment of Peptic Ulcers

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DOI: 10.23977/medsc.2024.050303 | Downloads: 6 | Views: 157

Author(s)

Ouyang Zhang 1, Zhipeng Xu 2

Affiliation(s)

1 Department of Clinical Medicine, North Sichuan Medical College, Nanchong, Sichuan, 637100, China
2 Department of Medical Imaging, North Sichuan Medical College, Nanchong, Sichuan, 637100, China

Corresponding Author

Ouyang Zhang

ABSTRACT

This paper provides a comprehensive review of the research progress on omeprazole in the treatment of peptic ulcers. Peptic ulcer is a common gastrointestinal disease with a complex pathogenesis and diverse clinical manifestations. Omeprazole, as a proton pump inhibitor, is widely used in the treatment of peptic ulcers by inhibiting gastric acid secretion. This paper systematically summarizes and discusses the pharmacological characteristics, clinical research progress, safety evaluation, and future development trends of omeprazole. The synthesis of various research results shows that omeprazole exhibits good efficacy and safety in the treatment of peptic ulcers, but there are still some issues that need further research and resolution. With the continuous advancement of science and technology, the future application prospects of omeprazole in the treatment of peptic ulcers will be broader.

KEYWORDS

Omeprazole, peptic ulcer, proton pump inhibitor, pharmacological characteristics

CITE THIS PAPER

Ouyang Zhang, Zhipeng Xu, Research Progress on Omeprazole in the Treatment of Peptic Ulcers. MEDS Clinical Medicine (2024) Vol. 5: 15-22. DOI: http://dx.doi.org/10.23977/medsc.2024.050303.

REFERENCES

[1] Yu. S S, O. D K, M. L K, et al. Kinetics of Omeprazole Release from Enteric Dosage Forms of Different Manufacturers [J]. Pharmaceutical Chemistry Journal, 2024, 57(10):1647-1654. 
[2] Nascimento S C L A, Martins B C I, Spósito L, et al. Indomethacin-omeprazole as therapeutic hybrids? Salt and co-amorphous systems enhancing physicochemical and pharmacological properties. [J]. International journal of pharmaceutics, 2024, 653123857-653123865. 
[3] Raza H, Abrar A, Ashraf A, et al. Design, Synthesis, Evaluation, and Molecular Docking Study of Ascorbic Acid Dual-Coated Omeprazole Pellets and the Antioxidative Effect of Ascorbic Acid on Omeprazole-Induced Renal Injury in an Animal Model. [J]. ACS omega, 2024, 9(1):1143-1155. 
[4] Adam M. Severe hyponatraemia peripartum associated with omeprazole therapy [J]. Obstetric Medicine, 2023, 16(4): 245-246. 
[5] Estrada R A C,Sánchez E,Córdova F A M, et al. Photosynthetic Efficiency in Green Bean Plants through the Application of Omeprazole and Melatonin at Low Doses [J]. International Journal of Plant Biology, 2023, 14(4): 864-878. 
[6] Habib M,Amin N,Saeed A, et al. Is the Addition of Sublingual Melatonin to Omeprazole Superior to Omeprazole Alone in the Management of Gastroesophageal Reflux Disease Symptoms: A Clinical Trial. [J]. The Turkish journal of gastroenterology: the official journal of Turkish Society of Gastroenterology, 2023, 34(12):1206-1211. 
[7] Juyoung S, Seulgi B. In vitro effects of omeprazole in combination with antifungal compounds against Malassezia pachydermatis. [J]. Veterinary medicine and science, 2023, 9(6):2594-2599. 
[8] Savaş K,Hassane L,Abhinay T, et al. Molecular insights into the corrosion inhibition mechanism of omeprazole and tinidazole: a theoretical investigation [J]. Molecular Simulation, 2023, 49(17):1632-1646.

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