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A Systematic Review and Meta-Analysis Comparing Endovascular, Laparoscopic, and Open Surgical Therapies for Varicocele

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DOI: 10.23977/medsc.2024.050217 | Downloads: 3 | Views: 70

Author(s)

Xianfei Liu 1, Zilin Lu 2, Mintao Li 3, Jian Zhou 2, Jian Dong 3, Zheng Shu 3

Affiliation(s)

1 Department of Vascular Surgery, The First Affiliated Hospital of the Naval Medical University, Shanghai, 200433, China
2 School of Health Science and Engineering, University of Shanghai for Science Technology, Shanghai, 200093, China
3 Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, 200082, China

Corresponding Author

Jian Zhou

ABSTRACT

Varicocele is a common vascular disease, which can seriously affect the physiological function of testis and lead to male infertility. The present study aims to systematically collect evidence on the treatment and observational outcomes of varicocele in infertile adult males, and to excavate the optimal treatment. This study was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) Statement and included only prospective randomized and non-randomized studies between January 1977 and September 2022. The outcomes of our observation included postoperative recurrence rate, major surgical complications, and postoperative pregnancy, the men with any-grade of varicocele were included as objects. We examined the outcomes of varicocele embolization with open surgery, laparoscopic embolization treatment, and laparoscopic treatment with open surgery in 2427 patients among 893 eligible articles and 21 trials. Offer guidelines for clinical practice.

KEYWORDS

Varicocele, Laparoscopic, Open Surgical Therapies, Meta-Analysis

CITE THIS PAPER

Xianfei Liu, Zilin Lu, Mintao Li, Jian Zhou, Jian Dong, Zheng Shu, A Systematic Review and Meta-Analysis Comparing Endovascular, Laparoscopic, and Open Surgical Therapies for Varicocele. MEDS Clinical Medicine (2024) Vol. 5: 105-111. DOI: http://dx.doi.org/10.23977/medsc.2024.050217.

REFERENCES

[1] Sasson DC, Kashanian JA. Varicoceles. JAMA. 2020; 323(21):2210. 
[2] Naughton CK, Nangia AK, Agarwal A. Pathophysiology of varicoceles in male infertility. Hum Reprod Update. 2001; 7(5):473-481. 
[3] Kim B, Park K, Rhee K. Heat stress response of male germ cells. Cell Mol Life Sci. 2013; 70(15):2623-2636. 
[4] Shah R, Agarwal A, Kavoussi P, et al. Consensus and Diversity in the Management of Varicocele for Male Infertility: Results of a Global Practice Survey and Comparison with Guidelines and Recommendations. World J Mens Health. 2023; 41(1):164-197.
[5] Kamischke A, Nieschlag E. Varicocele treatment in the light of evidence-based andrology. Hum Reprod Update. 2001; 7(1):65-69. 
[6] Moher D, Liberati A, Tetzlaff J, Altman DG; PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement [published correction appears in Int J Surg. 2010;8(8):658]. Int J Surg. 2010; 8(5):336-341. 
[7] Nieschlag E, Hertle L, Fischedick A, Behre HM. Treatment of varicocele: counselling as effective as occlusion of the vena spermatica. Hum Reprod. 1995 Feb; 10(2):347-353.
[8] Shahzad S, Shahid M W, Mughal M A, et al. Comparison of open sub-inguinal and microscopic sub-inguinal varicocelectomy for improvement of sperm parameters[J]. Pakistan Journal of Medical and Health Sciences, 2021, 15(10): 2882-2885.
[9] Nishio S, Yokoyama M, Takechi S, et al. Surgical treatment for varicocele: Comparison of clinical results of 4 methods[J]. Japanese Journal of Fertility and Sterility, 1995, 40(3): 286-290.
[10] Ouanes Y, Rahoui M, Chaker K, et al. Functional outcomes of surgical treatment of varicocele in infertile men: Comparison of three techniques[J]. Ann Med Surg (Lond), 2022, 78: 103937.
[11] Sayfan J, Soffer Y, Orda R. Varicocele treatment: Prospective randomized trial of 3 methods[J]. Journal of Urology, 1992, 148(5 I): 1447-1449.
[12] Sepúlveda L, Coimbra D, Lourenço M, et al. Varicocele treatment in patients up to 35 years old: A multicentric retrospective studycomparing 3 different techniques[J]. Arch Esp Urol, 2018, 71(6): 543-548.
[13] Yavetz H, Levy R, Papo J, et al. Efficacy of varicocele embolization versus ligation of the left internal spermatic vein for improvement of sperm quality[J]. International Journal of Andrology, 1992, 15(4): 338-344.
[14] Mongioì L M, Mammino L, Compagnone M, et al. Effects of Varicocele Treatment on Sperm Conventional Parameters: Surgical Varicocelectomy Versus Sclerotherapy[J]. Cardiovasc Intervent Radiol, 2019, 42(3): 396-404.
[15] Abdulmaaboud M R, Shokeir A A, Farage Y, et al. Treatment of varicocele: a comparative study of conventional open surgery, percutaneous retrograde sclerotherapy, and laparoscopy[J]. Urology, 1998, 52(2): 294-300.
[16] Pintus C, Rodriguez Matas M J, Manzoni C, et al. Varicocele in pediatric patients: comparative assessment of different therapeutic approaches[J]. Urology, 2001, 57(1): 154-157.
[17] Fayez A, El Shantaly K M, Abbas M, et al. Comparison of inguinal approach, scrotal sclerotherapy and subinguinal antegrade sclerotherapy in varicocele treatment: a randomized prospective study[J]. Urologia internationalis, 2010, 85(2): 200‐203.
[18] Jing Y X, Wang R H, Liu Z X, et al. Analysis of internal spermatic vein embolization through catheter versus laparoscopic high ligation in treatment of left varicocele[J]. Vascular, 2020, 28(5): 583-590.
[19] Feng R, Jiang J, Cheng D, et al. Clinical efficacy comparison of sclerosing embolization with 3% polidocanol and the microsurgical subinguinal varicocelectomy in primary varicocele patients[J]. Andrologia, 2022: e14530.
[20] Motta A, Caltabiano G, Pizzarelli M, et al. Varicocele, conventional laparoscopic ligation versus occluding balloon embolization [J]. Radiol Med, 2019, 124(5): 438-443.
[21] Sautter T, Sulser T, Suter S, et al. Treatment of varicocele: a prospective randomized comparison of laparoscopy versus antegrade sclerotherapy[J]. European urology, 2002, 41(4): 398‐400.
[22] Wickham A, Vu D, El-Arabi A, et al. Adolescent Varicocelectomy: Success at What Cost? Clinical Outcome and Cost Comparison of Surgical Ligation and Percutaneous Embolization[J]. Journal of Laparoendoscopic and Advanced Surgical Techniques, 2021, 31(8): 942-946.
[23] Binhazzaa M, Bounasr E, Perez G, et al. Comparison of subinguinal microsurgical varicocelectomy vs percutaneous embolization in infertile men[J]. Progres en urologie: journal de l'Association francaise d'urologie et de la Societe francaise d'urologie, 2016, 26(16): 1178-1184.
[24] May M, Johannsen M, Beutner S, et al. Laparoscopic surgery versus antegrade scrotal sclerotherapy: Retrospective comparison of two different approaches for varicocele treatment[J]. Eur Urol, 2006, 49(2): 384-387.
[25] Al-Kandari A M, Shabaan H, Ibrahim H M, et al. Comparison of outcomes of different varicocelectomy techniques: open inguinal, laparoscopic, and subinguinal microscopic varicocelectomy: a randomized clinical trial[J]. Urology, 2007, 69(3): 417-420.
[26] Watanabe M, Nagai A, Kusumi N, et al. Minimal invasiveness and effectivity of subinguinal microscopic varicocelectomy: a comparative study with retroperitoneal high and laparoscopic approaches[J]. Int J Urol, 2005, 12(10): 892-898.

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