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New advances in the causes and treatment of ectopic pregnancy: A review

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DOI: 10.23977/medsc.2024.050105 | Downloads: 26 | Views: 246


Xiaoli Liu 1, Caixia Liu 1, Yongpai Peng 1,2


1 Shenshan Medical Center, Memorial Hospital of Sun Yat-Sen University, Shanwei, China
2 Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China

Corresponding Author

Yongpai Peng


In recent years, the incidence of ectopic pregnancy has significantly increased, making it one of the common acute abdominal conditions in obstetrics and gynecology and a leading cause of maternal mortality. The etiology of ectopic pregnancy [1-4] is diverse, with inflammation being identified as a primary causative factor based on clinical statistics. Chronic salpingitis, particularly, is the most prevalent form of inflammation associated with ectopic pregnancy. Additionally, there is a close correlation with factors such as intrauterine devices, surgical history, and hormone levels. Therefore, effective measures should be taken to promote menstrual and antenatal hygiene, rigorously adhere to the surgical indications in obstetrics and gynecology, ensure aseptic procedures during surgery, and postoperatively focus on infection prevention to reduce the incidence. The current discussions on the treatment options for ectopic pregnancy include medical and surgical interventions. Notably, laparoscopic surgery [13] for treating ectopic pregnancy is characterized by its minimal invasiveness, high success rates, rapid postoperative recovery, fewer complications, and the preservation of patients' fertility. Hence, it is worthy of extensive clinical promotion.


Ectopic pregnancy; etiology; pelvic infection; MTX; laparoscopic surgical treatment


Xiaoli Liu, Caixia Liu, Yongpai Peng, New advances in the causes and treatment of ectopic pregnancy: A review. MEDS Clinical Medicine (2024) Vol. 5: 26-31. DOI:


[1] Orazulike N C, Konje J C. Diagnosis and management of ectopic pregnancy[J]. Women’s Health, 2013, 9(4): 373-385.
[2] Kathpalia S K, Arora D, Sandhu N, et al. Ectopic pregnancy: Review of 80 cases[J]. Medical Journal Armed Forces India, 2018, 74(2): 172-176.
[3] Murray H, Baakdah H, Bardell T, et al. Diagnosis and treatment of ectopic pregnancy[J]. Cmaj, 2005, 173(8): 905-912.
[4] Mukul L V, Teal S B. Current management of ectopic pregnancy[J]. Obstetrics and gynecology clinics of North America, 2007, 34(3): 403-419.
[5] Al Faraj Z M, Rubeya A A, Nafawi A M, et al. Ectopic Pregnancy Diagnosis and Management Approach: Literature Review[J]. Archives of Pharmacy Practice, 2019, 10(2): 9-12.
[6] Mullany K, Minneci M, Monjazeb R, et al. Overview of ectopic pregnancy diagnosis, management, and innovation[J]. Women's Health, 2023, 19: 17455057231160349.
[7] Ory S J. Ectopic pregnancy: Current evaluation and treatment[C]//Mayo Clinic Proceedings. Elsevier, 1989, 64(7): 874-877.
[8] Abdulkareem T A, Eidan S M. Ectopic pregnancy: diagnosis, prevention and management[M]//Obstetrics. IntechOpen, 2017.
[9] Nama V, Manyonda I. Tubal ectopic pregnancy: diagnosis and management[J]. Archives of gynecology and obstetrics, 2009, 279: 443-453.
[10] Alkatout I, Honemeyer U, Noé K G, et al. Diagnostic and treatment modalities for all localizations of ectopic pregnancy[J]. International Journal of Women’s Health and Reproduction Sciences, 2017, 5(2): 82-89.
[11] Barash J H, Buchanan E M, Hillson C. Diagnosis and management of ectopic pregnancy[J]. American family physician, 2014, 90(1): 34-40.
[12] Ankum W M, Mol B W J, Van der Veen F, et al. Risk factors for ectopic pregnancy: a meta-analysis[J]. Fertility and sterility, 1996, 65(6): 1093-1099.
[13] Abbott J, Emmans L S, Lowenstein S R. Ectopic pregnancy: ten common pitfalls in diagnosis[J]. The American journal of emergency medicine, 1990, 8(6): 515-522.
[14] Fylstra D L. Tubal pregnancy: a review of current diagnosis and treatment[J]. Obstetrical & gynecological survey, 1998, 53(5): 320-328.
[15] Barnes A N N B, Wennberg C N, Barnes B A. Ectopic pregnancy: incidence and review of determinant factors [J]. Obstetrical & Gynecological Survey, 1983, 38(6): 345-356.
[16] Shaw J L V, Dey S K, Critchley H O D, et al. Current knowledge of the aetiology of human tubal ectopic pregnancy[J]. Human reproduction update, 2010, 16(4): 432-444.
[17] Hoover K W, Tao G, Kent C K. Trends in the diagnosis and treatment of ectopic pregnancy in the United States[J]. Obstetrics & Gynecology, 2010, 115(3): 495-502.
[18] Parker V L, Srinivas M. Non-tubal ectopic pregnancy[J]. Archives of gynecology and obstetrics, 2016, 294: 19-27.
[19] Kirk E, Bottomley C, Bourne T. Diagnosing ectopic pregnancy and current concepts in the management of pregnancy of unknown location[J]. Human reproduction update, 2014, 20(2): 250-261.
[20] Yao M, Tulandi T. Current status of surgical and nonsurgical management of ectopic pregnancy[J]. Fertility and sterility, 1997, 67(3): 421-433.

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