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Progress in the treatment of gouty nephropathy with Chinese and Western medicine

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DOI: 10.23977/medcm.2024.060105 | Downloads: 4 | Views: 164

Author(s)

Li Xue 1, Xu Junjian 2

Affiliation(s)

1 Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, China
2 Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, China

Corresponding Author

Xu Junjian

ABSTRACT

With the continuous development of science and technology,the improvement of public quality of life and poor dietary habits,the incidence of hyperuricemia is increasing year by year,and the incidence of complications caused by it,such as gouty arthritis and gouty nephropathy,is also gradually increasing,and severe cases may even develop into end-stage renal disease,which seriously reduces people's quality of life and survival rate.At present,the purpose of reducing uric acid and protecting kidney is mainly achieved by combining traditional Chinese and western medicine.The Western medicine treatment of gouty nephropathy mainly adopts inhibition of uric acid synthesis,promotion of uric acid excretion or acceleration of uric acid decomposition to achieve the purpose of reducing uric acid, while taking into account the treatment of other complications such as kidney protection, blood pressure, hypoglycemia and lipid regulation. Through the combination of internal and external treatment such as syndrome differentiation, acupuncture or Chinese medicine application, Chinese medicine has the purpose of lowering uric acid to protect the kidney and delay the progression of the disease. This paper reviews the treatment of gouty nephropathy by Chinese and western medicine through reading domestic and foreign literatures, and provides reference materials for clinical treatment.

KEYWORDS

Gouty nephropathy; Traditional Chinese and Western medicine; Treatment; Research progress

CITE THIS PAPER

Li Xue, Xu Junjian, Progress in the treatment of gouty nephropathy with Chinese and Western medicine. MEDS Chinese Medicine (2024) Vol. 6: 31-37. DOI: http://dx.doi.org/10.23977/medcm.2024.060105.

REFERENCES

[1] Wu Jinhong, Zhang Libo, Wang Yao, et al. Professor Sun Yuzhi's experience in the treatment of gouty nephropathy by removing turbidity and promoting blood circulation [J]. Journal of Hunan University of Traditional Chinese Medicine, 2022
[2] Li Xuefei, Yin Haiqin, Luo Yusheng. Real world study on the effects of different uric acid lowering drugs on lipid metabolism [J]. Chinese Contemporary Medicine, 2023. 
[3] Kaewput Wisit, Thongprayoon Charat, Chewcharat Api, et al. Rate of kidney function decline and factors predicting progression of kidney disease in type 2 diabetes mellitus patients with reduced kidney function: A nationwide retrospective cohort study. [J]. Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2020, (6): 677-687. 
[4] Yanai Hidekatsu, Adachi Hiroki, Hakoshima Mariko, et al. Molecular Biological and Clinical Understanding of the Pathophysiology and Treatments of Hyperuricemia and Its Association with Metabolic Syndrome, Cardiovascular Diseases and Chronic Kidney Disease. [J]. International journal of molecular sciences, 2021, (17). 
[5] Liu Peng, Ma Guijie, Wang Yang, et al. Therapeutic effects of traditional Chinese medicine on gouty nephropathy: Based on NF-κB signalingpathways [J]. Elsevier BV: 114199. 
[6] Zhan Hongyi, Qing Song, Luo Liping, et al. Clinical study of different doses of febuxoat in the treatment of chronic kidney disease with hyperuricemia [J]. Chinese Journal of Nephropathy Research, 2018. 
[7] Zhang Yanzi. Study on the regulatory mechanism of NLRP_3 inflammasome signaling pathway in gouty nephropathy [D]. Southern Medical University, 2020
[8] Zhou Han, Liang Wei. Chronic kidney disease and hyperuricemia [J]. Journal of Clinical Internal Medicine, 2023. 
[9] Lu Wei, Zhou Yun. Research progress of the mechanism of renal injury associated with hyperuricemia [J]. Journal of Clinical Nephrology, 2023. 
[10] Xie Tingfei, Yuan Shuzhen, Sui Xiaolu, et al. Regulation mechanism of PI3K/AKT/NF-κB signaling pathway in human renal tubular epithelial cell inflammation induced by uric acid [J].Signal transduction and targeted therapy, 2021. 
[11] Sui Xiaolu, Xu Yunpeng, Zhang Yanzi, et al. The mechanism of PI3K/AKT/NF-κB signaling pathway in rats with uric acid nephropathy [J]. Journal of Practical Clinical Medicine, 2022. 
[12] Zhao Huiwen, Liu Chongkai, Fu Zhengju, et al. Expression and significance of IL-1β and IRAK-4 in uric acid nephropathy [J]. Advances in Modern Biomedicine, 2015. 
[13] Li Xiaoqian, Ji Wei, Qu Wei. Research progress of Chinese and Western medicine on uric acid nephropathy [J]. Journal of Practical Chinese Medicine Internal Medicine, 2021. 
[14] Wang Haiyan. Kidney disease study [J]. People's medical publishing house, 2008, 10 (01): 14-19. 
[15] Xie Zhaohu, XieJing, Li Zhaofu, etc. Advances in the treatment of gouty nephropathy with Chinese and Western medicine [J]. Chinese Journal of Traditional Chinese Medicine, 2019. 
[16] Wang Ling, Peng Ai. Interpretation of Diagnosis and treatment Guidelines for hyperuricemia and gout in China (2019) [J]. Western Medicine, 2021. 
[17] Stamp Lisa-K, Farquhar Hamish, Pisaniello Huai-Leng, et al. Management of gout in chronic kidney disease: a G-CAN Consensus Statement on the research priorities[J]. Nature Reviews Rheumatology, 2021: 633-641. 
[18] Mei Yongsheng, Dong Bingzi, Geng Zhuang, et al. Excess Uric Acid Induces Gouty Nephropathy Through Crystal Formation: A Review of Recent Insights. [J]. Frontiers in endocrinology, 2022: 911968. 
[19] Bardin Thomas, Richette Pascal. Impact of comorbidities on gout and hyperuricaemia: an update on prevalence and treatment options. [J]. BMC medicine, 2017, (1): 123. 
[20] Feng Wenwen, Cui Dai, Yang Tao. Key points of Chinese Guidelines for Diagnosis and Treatment of hyperuricemia and gout (2019) [J]. Journal of Clinical Internal Medicine, 2020. 
[21] Kanda Eiichiro, Muneyuki Toshitaka, Kanno Yoshihiko, et al. Uric acid level has a U-shaped association with loss of kidney function in healthy people: a prospective cohort study. [J]. PloS one, 2015, (2): e0118031. 
[22] Borghi C, Domienik-Karłowicz J, Tykarski A, Widecka K, Filipiak KJ, Jaguszewski MJ, Narkiewicz K, Mancia G. Expert consensus on diagnosis and treatment of hyperuricemia in patients with chronic kidney disease in China [J]. Clinical Medical Research and Practice, 2017. 
[23] Zhang Jingchao, Lin Yan. Research progress of Chinese medicine treatment of gouty nephropathy [J]. Clinical Research of Chinese Medicine, 2019. 
[24] Gu Huixuan, Jin Feng, Ma Ruifang. Research progress of TCM treatment of gouty nephropathy [J]. World Latest Medical Information Digest, 2019. 
[25] Guo Rong, Zhang Xikui. Professor Zhang Xikui's experience in differentiating and treating gouty nephropathy [J]. Fujian Traditional Chinese Medicine, 2019. 
[26] Zhu Meifeng, Zhang Ling, Lu Jiawei, et al. Chen Dai's experience in the treatment of gouty nephropathy [J]. Jiangsu Chinese Medicine, 2021. 
[27] Tang Kexin, LI Xiaoqing, Luo Xuewen, et al. Clinical experience of Pizhiheng in the treatment of gouty nephropathy [J]. Chinese Folk Therapy, 2022. 
[28] Li Xiaoyan, Xing Haiyan, Ren Yongpeng. Professor WANG Zimin's experience in the treatment of gouty nephropathy by staging and classification [J]. Chinese Medicine Research, 2019. 
[29] Ren Yongpeng, Hua Qiong, Liu Yanyan, et al. Li Peixu's experience in treating gouty nephropathy from dampness, heat, blood stasis and poison [J]. New Chinese Medicine, 2019. 
[30] He Xun, Zhong Ying. Zhong Ying's experience in treating gouty nephropathy complicated with chronic renal dysfunction [J]. Hunan Journal of Traditional Chinese Medicine, 2018. 
[31] Wei Jinhua, Hu Baofeng, Li Jiyuan, et al. Effect of invigorating spleen and removing blood stasis on renal interstitial fibrosis in patients with uric acid nephropathy [J]. Primary Chinese Medicine, 2022
[32] Li Yarong, Chen Rui. Application of Chinese medicine patch in patients with gout [J]. Guizhou Medicine, 2023. 
[33] Li Mengyuan. Comparative observation of clinical efficacy of acupoint application and external application of Chinese medicine in the treatment of acute gouty arthritis [D]. Chongqing Medical University, 2022
[34] Yuan Xiao, Chen Xialiang. Understanding of acute gouty arthritis in traditional Chinese Medicine [J]. Hubei Journal of Traditional Chinese Medicine, 2019. 
[35] Shen Fang, Tang Yanghua, Xu Canda, et al. Therapeutic effect of Supplemented Sihuang Paste on acute gouty arthritis [J]. Chinese Journal of Integrated Traditional and Western Medicine Surgery, 2020. 
[36] Liu Huan, Zhou Shengyuan. Research progress of acupuncture in the treatment of gouty arthritis [J]. Chinese Medical Forum, 2022. 
[37] Zheng Lu, Qi Xiangrong, Han Yun, et al. Research progress of acupuncture in the treatment of hyperuricemia [J]. Chinese Emergency Medicine, 2021. 
[38] Liu Dunyu, Lin Yong, Li Guangzhen. Observation of clinical efficacy of moxibustion in the treatment of chronic gouty arthritis [J]. Inner Mongolia Traditional Chinese Medicine, 2017. 
[39] Wen Xianhua, Mo Lisha, Yu Jianping. Professor Yu Jianping's experience in the treatment of gouty nephropathy by clearing heat and diuresis combined with enema of Chinese medicine [J]. Asia Pacific Traditional Medicine, 2018. 
[40] Zhao Hong, Chai Guifang, Liu Yingfei, et al. Protective effect and mechanism of Psyllium seed decoction on rats with gouty nephropathy [J]. Chinese Journal of Experimental Formulae, 2018. 
[41] Bai Li, Wei Xiangping, Li Ning, et al. Protective effect of total flavonoids of Peony flower on mice model of gouty nephropathy [J]. Pharmacology and Clinic of Chinese Materia Medica, 2022. 
[42] Jin Wenmin, Sun Zhihua, Qin Fei. Regulation of reactive oxygen/nuclear factor-κB signaling pathway and renal protection by Yougui Yin in rats with gouty nephropathy [J]. Chinese Journal of Integrative Nephropathy, 2021. 
[43] Li Yuxuan, Song Lin, Yu Xuecheng, et al. Study on the mechanism of Atractylodes Baihu Decoction on hyperuricemia nephropathy mice [J]. Sichuan Traditional Chinese Medicine, 2019. 
[44] Xiang Huilong. Study on the mechanism of action of baicalin and baicalin in antiuric acid nephropathy [D]. Wuhan University of Light Industry, 2021.

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