Study on the pathogenesis and treatment of carotid atherosclerosis from "phlegm, blood stasis and toxicity"
DOI: 10.23977/medcm.2023.051019 | Downloads: 4 | Views: 244
Author(s)
Meiru Yi 1, Yanni Liu 2, Chaofan Li 1, Qing He 1
Affiliation(s)
1 Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712046, China
2 Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi, 712000, China
Corresponding Author
Yanni LiuABSTRACT
Carotid atherosclerosis is an independent risk factor for the occurrence of ischemic stroke, posing a serious threat to human health. Although modern medicine has achieved some success in the treatment of plaque, there are problems such as large side effects and high recurrence rate. According to the characteristics of carotid atherosclerosis, this paper discusses the etiology and pathogenesis of carotid atherosclerosis in traditional Chinese medicine, and concludes that "phlegm", "blood stasis", and "toxicity" run through the development of atherosclerotic diseases, and that "phlegm", "blood stasis", and "toxicity" are always present. It is believed that "phlegm", "blood stasis" and "toxicity" run through the development of atherosclerosis, and "phlegm, blood stasis and toxicity" is the core mechanism of the disease. In clinical treatment, "resolving phlegm and expelling stasis, detoxifying and clearing the veins" should be the main focus. The prevention and treatment of carotid atherosclerosis based on the theory of "phlegm, blood stasis and toxicity inter-conjugation" provides new ideas and methods for Chinese medicine to prevent and treat carotid atherosclerosis and its complications.
KEYWORDS
Phlegm; blood stasis and toxicity; Carotid Atherosclerosis; etiology; pathogenesisCITE THIS PAPER
Meiru Yi, Yanni Liu, Chaofan Li, Qing He, Study on the pathogenesis and treatment of carotid atherosclerosis from "phlegm, blood stasis and toxicity". MEDS Chinese Medicine (2023) Vol. 5: 131-136. DOI: http://dx.doi.org/10.23977/medcm.2023.051019.
REFERENCES
[1] Aldana-Bitar J, Bhatt DL, Budoff MJ. Regression and stabilization of atherogenic plaques. Trends Cardiovasc Med. 2023 Jul 24:S1050-1738(23)00063-4.
[2] Lim EY, Cho AH. Dynamic Changes of Carotid Atherosclerosis and Their Relation with Stroke Recurrence in Patients with Stroke or Transient Ischemic Attack. Curr Neurovasc Res. 2022;19(3):303-310.
[3] Zhao FF, Gao HY, Gao Y, et al. A Correlational Study on Cerebral Microbleeds and Carotid Atherosclerosis in Patients with Ischemic Stroke. J Stroke Cerebrovasc Dis. 2018 Auget al. ;27(8):2228-2234.
[4] SHA Yuejiao,LI Yunlun,MI Deyang. Discussion on Differentiation and Treatment of Carotid Atherosclerosis from Vessel Impediment[J]. Journal Of Shandong University Of TCM.2020 JUL;44(04):356-359.
[5] ZHANG Yijia,FAN Ke,CUI Xiaoshu, et al.Clinical Research Progress of Chinese Medicine in the Treatment of Atherosclerosis[J].Acta Chinese Medicine.2020;35(09):1908-1912.
[6] ZHANG Zhang,QIU Le,WANG Hebao, et al.Discussion on the Form and Meaning of "Phlegm"in Traditional Chinese Medicine[J].Journal of Traditional Chinese Medicine.2019,60(10):811-814.
[7] Shengwan W , Jingqing H , Lijie J ,et al.Exploring the Molecular Mechanism of the Formation of the Syndrome of Intermingled Phlegm and Blood Stasis[J].Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology, 2016.
[8] Baba M, Maris M, Jianu D, et al. The Impact of the Blood Lipids Levels on Arterial Stiffness. Journal of Cardiovascular Development and Disease. 2023; 10(3):127.
[9] LI Quan,ZHANG Xuexin,LIU Yanju.Clinical observation of Huatan Quzhuo prescription in the treatment of carotid atherosclerosis plaque with spleen deficiency and phlegm turbidity repression type[J].Hebei J TCM.2019;41(01):42-46.
[10] GUO Suihuai,ZHANG Lijun.Influence of Ditan Decoction on Lipid Metabolism,Oxidant Stress and Inflammatory Cytokines in Atherosclerosis Rabbits.Journal of Hubei University of Chinese Medicine.2016,18(01):8-11.
[11] YANG Li-na, LI Ming, DONG Quan-wei,et al.Textural research of pulse bi[J].China Journal of Traditional Chinese Medicine and Pharmacy ,2019,34(01):75-77.
[12] Libby P,Tabas I,Fredman G,et al . Inflammation and its resolution as determinants of acute coronary syndromes[J]. Circ Res,2014,114 (12 ) :1867 -1879
[13] WU Qian,LI Lanlan ,CAO Linlin,et al .Medication laws of simultaneous treatment for phlegm and blood stasis in treating atherosclerosis based on data mining[J].China Medical Herald.2023,20(06):119-122+144.
[14] Yu Wenzhen,Chen Shi ,Zhang Yongliang,et al .Effect of Activating Blood and Resolving Stasis Therapy on Injuried Vascular wnt / β-catenin Signal Pathway of Rats with Carotid Atherosclerosis[J].Word Chinese Medicine. 2016, 11(03): 498-501.
[15] CHI Xiansu,LIANG Xiao,WEI Jingjing,et al.Treatment of ischemic stroke from perspective of phlegm blood stasis and poison based on theory of turbid blood[J].Shaanxi Journal of Traditional Chinese Medicine.2023,44(07):917-921.
[16] Wang Kebin,Ma Lian,Wu Shengxian.Treatment of atherosclerotic vulnerable plaques from the perspective of "toxic damage to the veins"[J].Acta Chinese Medicine and Pharmacology.2018,46(05):5-7.
[17] YANG Ronglai,WANG Fengrong,SHI Haijiao,et al.Discussion on"Sputum,Stasis,Poison"of the Inflammatory Response of Daqaihu Decoction in the Preventive Treatment of Atherosclerosis[J].Journal Of Liaoning University Of TCM.2020,22(08):94-96.
[18] Jiang Mianjun,SHi Zhongliang,Gu Huiwen.Discussion on the pathogenesis of atherosclerosis based on phlegm and stasis theory[J].Chinese Journal Of Integrative Medicine On Cardio-Cerebrovascular Disease. 2022,20(11):2098-2100.
[19] Tian Xin,Xie Huaning,Fan Hong,et al.Analysis on the connotation of "phlegm, blood stasis and toxin combined" syndrome of thoracic obstruction treated by traditional Chinese medicine master Lei Zhongyi[J].Clinical Medicine Research and Practice.2022,7(22):1-3+19.
[20] Yu Junsheng,Wang Yanlin.Discussion on correlation of phlegm ,blood stasis and poison[J].Shandong Journal of Traditional Chinese Medicine.2000(06):323-325.
Downloads: | 4224 |
---|---|
Visits: | 167357 |
Sponsors, Associates, and Links
-
MEDS Clinical Medicine
-
Journal of Neurobiology and Genetics
-
Medical Imaging and Nuclear Medicine
-
Bacterial Genetics and Ecology
-
Transactions on Cancer
-
Journal of Biophysics and Ecology
-
Journal of Animal Science and Veterinary
-
Academic Journal of Biochemistry and Molecular Biology
-
Transactions on Cell and Developmental Biology
-
Rehabilitation Engineering & Assistive Technology
-
Orthopaedics and Sports Medicine
-
Hematology and Stem Cell
-
Journal of Intelligent Informatics and Biomedical Engineering
-
MEDS Basic Medicine
-
MEDS Stomatology
-
MEDS Public Health and Preventive Medicine
-
Journal of Enzyme Engineering
-
Advances in Industrial Pharmacy and Pharmaceutical Sciences
-
Bacteriology and Microbiology
-
Advances in Physiology and Pathophysiology
-
Journal of Vision and Ophthalmology
-
Frontiers of Obstetrics and Gynecology
-
Digestive Disease and Diabetes
-
Advances in Immunology and Vaccines
-
Nanomedicine and Drug Delivery
-
Cardiology and Vascular System
-
Pediatrics and Child Health
-
Journal of Reproductive Medicine and Contraception
-
Journal of Respiratory and Lung Disease
-
Journal of Bioinformatics and Biomedicine