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Acupoint Catgut Embedding Combined with Time-restricted Feeding for the Treatment of Simple Obesity: A Randomized Controlled Trial

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DOI: 10.23977/medcm.2023.051009 | Downloads: 14 | Views: 245

Author(s)

Xueyi He 1, Jiao Qiu 1, Shijing Lian 1, Xiao Wu 2

Affiliation(s)

1 Department of Acupuncture, Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan, 646099, China
2 Department of Prevention and Treatment Center, Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, Sichuan, 646099, China

Corresponding Author

Xiao Wu

ABSTRACT

Obesity is known as being closely related to a variety of diseases and harm to health. Obesity has become a worldwide major public health, affecting adults, adolescents, and children of both genders.  In recent years, acupoint catgut embedding(ACE) with other therapies for the treatment of obesity has attracted attention, studies have shown combination therapies have more significant effect. Meantime, time-restricted feeding(TRF), as a new research hot-spot, has been confirmed to improve metabolism and control obesity by regulating human rhythm. But there have been not clear trials of those two combinations. This study aims to explore the clinical effects of acupoint catgut embedding combine with time-restricted feeding in the treatment of simple obesity people. This study is a parallel-design, randomized, and controlled clinical study. A total of 162 participants will be randomly assigned to three different groups in a 1:1:1 ratio. Participants in the ACE group will receive ACE treatment, and participants in the ACE + TRF group will have time-restricted eating on base of the ACE treatment, with a daily eating time of 8am-6pm. The control group received no treatment during the experiment. All participants will receive treatment for 12 weeks, and are followed for another 12 weeks. The primary outcome is the participants' weight and body mass index(BMI). Secondary indicators are participants' waist circumference, hip circumference, waist-hip ratio (WHR), body fat percentage (BFR), blood lipids, blood sugar, and uric acid. Trial efficacy will be assessed by measurement results.

KEYWORDS

Simple obesity; acupoint catgut embedding; time-restricted feeding; protocols

CITE THIS PAPER

Xueyi He, Jiao Qiu, Shijing Lian, Xiao Wu, Acupoint Catgut Embedding Combined with Time-restricted Feeding for the Treatment of Simple Obesity: A Randomized Controlled Trial. MEDS Chinese Medicine (2023) Vol. 5: 55-62. DOI: http://dx.doi.org/10.23977/medcm.2023.051009.

REFERENCES

[1] Lobstein T, Jackson-Leach R. Planning for the worst: estimates of obesity and comorbidities in school-age children in 2025 [J]. Pediatric obesity, 2016, 11(5):321-325. 
[2] Dehlin Mats, Jacobsson Lennart, Roddy Edward, et al. Global epidemiology of gout: prevalence, incidence, treatment patterns and risk factors [J]. Nature reviews. Rheumatology, 2020, 16(7):380-390. 
[3] Piché Marie-Eve, Tchernof André, Després Jean-Pierre, et al. Obesity Phenotypes, Diabetes, and Cardiovascular Diseases [J]. Circulation research, 2020, 126(11):1477-1500. 
[4] Wu Yangyang, Lei Puchao, Li Lingling, et al. The Association Between Abdominal Obesity and Diabetes among Middle-aged and Older Adults with Normal BMI [J]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2021, 52(2):340-344. 
[5] Prospective Studies Collaboration. Body-mass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies [J]. The Lancet, 2009, 373(9669):1083-1096. 
[6] Sturm R, An R., Maroba J, et al. The effects of obesity, smoking, and excessive alcohol intake on healthcare expenditure in a comprehensive medical scheme : research [J]. South African Medical Journal, 2013, 103(11):840-844. 
[7] Monnier Louis, Schlienger Jean Louis, Colette Claude, et al. The obesity treatment dilemma: Why dieting is both the answer and the problem? A mechanistic overview [J]. Diabetes & Metabolism, 2020, 47(3): 101192. 
[8] Celik O, Yildiz B O. Obesity and physical exercise [J]. Minerva Endocrinology, 2021, 46(2): 131-144. 
[9] John Sharretts, Ovidiu Galescu, Shanti Gomatam, et al. Cancer Risk Associated with Lorcaserin — The FDA’s Review of the CAMELLIA-TIMI 61 Trial [J]. New England Journal of Medicine, 2020, 383(11):1000-1002. 
[10] Coulter Ann A, Rebello Candida J, Greenway Frank L, et al. Centrally Acting Agents for Obesity: Past, Present, and Future [J]. Drugs, 2018, 78(11):1113-1132.
[11] Chen Feng, Wu Song, Zhang Yan, et al. Effect of acupoint catgut embedding on TNF-alpha and insulin resistance in simple obesity patients [J]. Zhen ci yan jiu = Acupuncture research, 2007, 32(1):49-52. 
[12] Chen I-J, Yeh Y-H, Hsu C-H. Therapeutic effect of acupoint catgut embedding in abdominally obese women: a randomized, double-blind, placebo-controlled study [J]. Journal of Women’s Health (2002), 2018, 27(6): 782-790. 
[13] Valter D. Longo, Satchidananda Panda. Fasting, Circadian Rhythms, and Time-Restricted Feeding in Healthy Lifespan [J]. Cell Metabolism, 2016, 23(6):1048-1059. 
[14] Megumi Hatori, Christopher Vollmers, Amir Zarrinpar, et al. Time-Restricted Feeding without Reducing Caloric Intake Prevents Metabolic Diseases in Mice Fed a High-Fat Diet [J]. Cell Metabolism, 2012, 15(6):848-860. 
[15] Sherman Hadas, Genzer Yoni, Cohen Rotem, et al. Timed high-fat diet resets circadian metabolism and prevents obesity [J]. FASEB journal: official publication of the Federation of American Societies for Experimental Biology, 2012, 26(8):3493-3502. 
[16] Liu Zhigang, Dai Xiaoshuang, Zhang Hongbo, et al. Gut microbiota mediates intermittent-fasting alleviation of diabetes-induced cognitive impairment [J]. Nature communications, 2020, 11(1):855. 
[17] Li Guolin, Xie Cen, Lu Siyu, et al. Intermittent Fasting Promotes White Adipose Browning and Decreases Obesity by Shaping the Gut Microbiota [J]. Cell Metabolism, 2017, 26(5):801-801. 
[18] Kawai T, Autieri M V, Scalia R. Adipose tissue inflammation and metabolic dysfunction in obesity [J]. American Journal of Physiology, 2021, 320(3): C375-C391. 
[19] Engin Atilla. The Definition and Prevalence of Obesity and Metabolic Syndrome [J]. Advances in experimental medicine and biology, 2017, 960:1-17. 
[20] Li Donghui, Tang Weiwei, Wang Yanyan, et al. An overview of traditional Chinese medicine affecting gut microbiota in obesity [J]. Frontiers in Endocrinology, 2023, 14:1149751-1149751. 
[21] Guo Li, Fu Xin, Jiang Zhengming, et al. Acupoint massage nursing conducive to improve curative effect of the obesity patients who are complicated with hypertension and are treated by oral drugs [J]. International journal of clinical and experimental medicine, 2015, 8(7):11727-11733. 
[22] Kim Koh-Woon, Yoo Hye Hyun, Cho Jae-Heung, et al. Effects of acupuncture on serum metabolic parameters in premenopausal obese women: study protocol for a randomized controlled trial [J]. Trials, 2015, 16(1):327. 
[23] Wang Li, Yu Chaochao, Li Jia, et al. Mechanism of Action of Acupuncture in Obesity: A Perspective From the Hypothalamus [J]. Frontiers in Endocrinology, 2021, 12:632324-632324. 
[24] Chen Xia, Huang Wei, Wei Dan, et al. Effect of Acupoint Catgut Embedding for Middle-Aged Obesity: A Multicentre, Randomised, Sham-Controlled Trial [J]. Evidence-Based Complementary and Alternative Medicine, 2022, 2022:4780019-4780019. 
[25] Jessica M Garcia-Vivas, Carlos Galaviz-Hernandez, Flavia Becerril-Chavez, et al. Acupoint catgut embedding therapy with moxibustion reduces the risk of diabetes in obese women [J]. Journal of Research in Medical Sciences, 2014, 19(7):610-616. 
[26] Yu Liqing, Liao Yanjun, Wu Huangan, et al. Effects of electroacupuncture and Chinese kidney-nourishing medicine on polycystic ovary syndrome in obese patients [J]. Journal of Traditional Chinese Medicine, 2013, 33(3):287-293. 
[27] Amandine Chaix, Terry Lin, Hiep D. Le, et al. Time-Restricted Feeding Prevents Obesity and Metabolic Syndrome in Mice Lacking a Circadian Clock [J]. Cell Metabolism, 2019, 29(2):303-319. 
[28] Hu Dandan, Xie Zhibo, Ye Yuqian, et al. The beneficial effects of intermittent fasting: an update on mechanism, and the role of circadian rhythm and gut microbiota [J]. Hepatobiliary Surgery and Nutrition, 2020, 9(5):597-602.

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