Author(s)

Yuan Yan

Corresponding Author

Yuan Yan

ABSTRACT

Fibromyalgia (FM) is a chronic pain syndrome accompanied by a range of other symptoms. Cognitive impairment is a core sign and symptom in FM, yet sometimes neglected, with a profound effect on instrumental things to do of each day living. The occurrence may affect people of all ages, although it is most frequent in the woman middle-aged. Working memory, attention, and executive function are the most frequently affected cognitive domains. Neuroimaging studies show that atrophy and changeable functional connectivity of grey matter are related to cognitive dysfunction. Currently, the absence of clinically effective biomarkers for detection and quantification of cognitive symptoms makes traditional neuro-psychiatrical scales and tests remain the most important tools in the assessment of cognitive impairment in FM. This review addresses the prevalence, abnormalities, neuroimaging of cognitive impairments in patients with FM while explaining currently available assessments and therapeutic options.

KEYWORDS

Cognitive impairment Fibromyalgia neuroimaging neuropsychiatrical assessment therapeutic options