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Effect of silk fibroin dressing on postoperative wound healing

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DOI: 10.23977/medbm.2026.040107 | Downloads: 1 | Views: 141

Author(s)

Xu Qing 1, Shen Jiexing 1, Ye Jie 1, Chen Shuyu 1, Shu Ping 1, Guo Guodong 1

Affiliation(s)

1 Jianhu People's Hospital, Yancheng, Jiangsu, 224700, China

Corresponding Author

Guo Guodong

ABSTRACT

This study aims to observe the clinical effect and safety of silk fibroin dressing, liquid dressing, and conventional collagen dressing for postoperative wound healing in sports medicine surgeries. We selected 144 patients who had sports medicine surgeries. They were randomly divided into Trial Group 1 (n=48), Trial Group 2 (n=48), and a Control Group (n=48). Trial Group 1 used silk fibroin dressing (Fuxiang Sitai Medical Technology). Trial Group 2 used liquid dressing (Guangzhou Beiaojiyin Biotechnology). The Control Group used conventional collagen dressing. The application scope of the two dressings in the trial group was non-chronic wounds, including suture wounds after surgery, laser surgery, small wounds, abrasion, and cutting wounds. We compared the incision healing grade, Vancouver Scar Scale (VSS) score, patient satisfaction, and adverse reactions among the three groups. The results showed that 47 patients in Trial Group 1, 48 patients in Trial Group 2, and 47 patients in the Control Group got Grade A healing. The difference had no statistical significance (P>0.05). However, 3 months after the operation, the VSS scar score in Trial Group 1 (2.39 ± 0.82) and Trial Group 2 (2.44 ± 0.79) was significantly lower than that in the Control Group (6.86 ± 1.32) (P<0.05). The patient satisfaction rate in Trial Group 1 (93.75%) and Trial Group 2 (95.83%) was significantly higher than the Control Group (75.00%) (P < 0.05). The incidence of adverse reactions was 4.17% in Trial Group 1, 8.33% in Trial Group 2, and 10.42% in the Control Group. The difference had no statistical significance (x2=6.115, P>0.05). In conclusion, silk fibroin dressing and liquid dressing have the same good incision healing effect as conventional collagen dressing. But they can significantly reduce scar formation and improve patient satisfaction safely. They are very good choices for postoperative wound care in sports medicine.

KEYWORDS

Silk fibroin dressing; Sports medicine; Wound healing; Liquid dressing; Hypertrophic scar; Vancouver Scar Scale

CITE THIS PAPER

Xu Qing, Shen Jiexing, Ye Jie, Chen Shuyu, Shu Ping, Guo Guodong. Effect of silk fibroin dressing on postoperative wound healing. MEDS Basic Medicine (2026). Vol. 4, No. 1, 52-57. DOI: http://dx.doi.org/10.23977/medbm.2026.040107.

REFERENCES

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