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  4. Vol 1, Issue 1, 2024

Comparative Study on the Absorption Rate of Nano-Micellar Biphasic Astaxanthin Versus Synthetic Astaxanthin in Healthy Adults

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DOI: 10.23977/nanodd.2024.010101 | Downloads: 5 | Views: 46

Author(s)

Naizhuang Wang 1, Jingjing Dai 1, Binbin Song 1, Waifun Moka 1

Affiliation(s)

1 IEternal Grace PTE.LTD, 128 Tuas South Avenue 3#01-05, JTC Space @ Tuas Biomedical Park, 637370, Singapore

Corresponding Author

Jingjing Dai

ABSTRACT

This study compared the absorption rates of nano-micellar biphasic astaxanthin and synthetic astaxanthin in a group of eighteen healthy adults. Participants were randomly assigned to receive either nano-micellar astaxanthin or synthetic astaxanthin, with a daily intake of 6 mg of astaxanthin for seven consecutive days. Blood samples were collected on days 1, 3, and 7 to measure plasma astaxanthin concentrations for assessing absorption rates. The results revealed significantly higher blood drug concentrations of nano-micellar astaxanthin compared to synthetic astaxanthin, with Cmax and AUC values markedly higher than those of synthetic astaxanthin. Specifically, the Cmax of the nano-micellar astaxanthin group was 12.10 times that of the synthetic astaxanthin group, and the AUC was 11.47 times that of the synthetic astaxanthin group. The enhanced absorption of nano-micellar astaxanthin indicates strengthened antioxidant effects and potential health benefits. These findings support the use of nano-micellar biphasic astaxanthin in dietary supplements, offering promise for improved cardiovascular health, immune function, and reduced oxidative stress.

KEYWORDS

Astaxanthin, Absorption rate, Nano-micellar, Bioavailability

CITE THIS PAPER

Naizhuang Wang, Jingjing Dai, Binbin Song, Waifun Moka, Comparative Study on the Absorption Rate of Nano-Micellar Biphasic Astaxanthin Versus Synthetic Astaxanthin in Healthy Adults. Nanomedicine and Drug Delivery (2024) Vol. 1: 1-4. DOI: http://dx.doi.org/10.23977/nanodd.2024.010101.

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