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  4. Vol 1, Issue 2, 2023

Mechanism Study on the Treatment of Pelvic Pain in Endometriosis by Qu Yu Jie Du Xiao Zheng Decotion in Combination with Dextroprogesterone

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DOI: 10.23977/medbm.2023.010214 | Downloads: 8 | Views: 270

Author(s)

Chen Wang 1, Mengjie Chen 1

Affiliation(s)

1 Xi'an Hospital of Traditional Chinese Medicine, Xi'an 710021, Shaanxi, China

Corresponding Author

Mengjie Chen

ABSTRACT

This study aimed to evaluate the clinical efficacy and effect on serum levels of PGE2, NGF and TNF-α of the combination of Qu Yu Jie Du Xiao Zheng Decotion and Dydrogesterone in treating pelvic pain in patients with endometriosis. Sixty patients were randomly divided into three groups: Chinese medicine group, Western medicine group, and combination group. After treatment, the combination group showed significant relief of pain, and the apparent efficacy of menstrual pain, pelvic pressure pain, and palpable nodules was 70%, 83.33%, and 61.54%, respectively, which was significantly higher than that of the other two groups. There were significant differences in serum TNF-α, NGF and PGE2 levels among the three groups after treatment. The conclusion was that the combination of Qu Yu Jie Du Xiao Zheng Decotion and Dydrogesterone could significantly improve the immune function of patients with endometriosis, regulate levels of nerve growth factor, tumor necrosis factor, and prostaglandin E2, thereby relieving pain.

KEYWORDS

Endometriosis, Qu Yu Jie Du Xiao Zheng Decotion, Deferiprone, Tumor Necrosis Factor, Prostaglandins, Nerve Growth Factor

CITE THIS PAPER

Chen Wang, Mengjie Chen, Mechanism Study on the Treatment of Pelvic Pain in Endometriosis by Qu Yu Jie Du Xiao Zheng Decotion in Combination with Dextroprogesterone. MEDS Basic Medicine (2023) Vol. 1: 89-96. DOI: http://dx.doi.org/10.23977/medbm.2023.010214.

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