Education, Science, Technology, Innovation and Life
Open Access
Sign In

New technology and application of microfluidic technology in biological sample analysis

Download as PDF

DOI: 10.23977/analc.2023.020116 | Downloads: 9 | Views: 435

Author(s)

Zixia Feng 1

Affiliation(s)

1 The Hong Kong University of Science and Technology, Hong Kong, 999077, China

Corresponding Author

Zixia Feng

ABSTRACT

Microfluidic technology has become a revolutionary potential technology in the field of biological sample analysis. This paper summarizes the new technology and application of microfluidic technology in biological sample analysis, emphasizing its key role in high-throughput analysis, single-cell analysis, personalized medicine, environmental monitoring and future development trends. In the new technology and application of microfluidic technology, high throughput analysis is a prominent direction. Microfluidic system can effectively process a large number of biological samples, reducing the time-consuming and cost of experiments. This provides powerful tools in the fields of genomics, protein omics and drug screening, and provides new opportunities for scientific research and clinical diagnosis. Single cell analysis is another remarkable application of microfluidic technology. Microfluidic chip can efficiently analyze a single cell and reveal cell heterogeneity and disease mechanism. This provides a profound insight for cancer research, immunology and neuroscience. In the future, microfluidic technology will continue to promote the development of biological sample analysis. Multifunctional chips, portable applications and the combination with machine learning will provide researchers with more tools and methods to deeply understand the complexity of biology.

KEYWORDS

Microfluidic technology; application; biological sample analysis

CITE THIS PAPER

Zixia Feng, New technology and application of microfluidic technology in biological sample analysis. Analytical Chemistry: A Journal (2023) Vol. 2: 123-130. DOI: http://dx.doi.org/10.23977/analc.2023.020116.

REFERENCES

[1] Yu Ke. (2013). Microfluidic-based cell assay for biomedical application. Recent Patents on Biomedical Engineering, 6(3), 195-202.
[2] Zhao, X., Wang, G., Shao, S., Meng, Q., & Zhang, C. (2021). Terahertz characteristics of magnetic fluid based on microfluidic technology. International Journal of Optics, 2021(8), 1-8.
[3] Mary, P., Dauphinot, L., Nadège Bois, Potier, M. C., & Tabeling, P. (2011). Analysis of gene expression at the single-cell level using microdroplet-based microfluidic technology. Biomicrofluidics, 5(2), 24109.
[4] Zhang, J., Sun, J., Li, B., Yang, C., & Liu, K. (2020). Robust biological fibers based on widely available proteins: facile fabrication and suturing application. Small, 16(8), 1907598.
[5] Fan, J. F., Zhu, Y., Shi, X. T., Fang, Q., & Huang, J. (2012). Microfluidic sequential injection analysis system based on polydimethylsiloxane (pdms) chip with integrated pneumatic-actuated valves. SCIENCE CHINA Chemistry, 55(4), 531-536.
[6] Jeremy, Masbou, David, Point, Jeroen, & E., et al. (2013). Application of a selective extraction method for methyl mercury compound specific stable isotope analysis (mehg-csia) in biological materialsf. Journal of Analytical Atomic Spectrometry, 28(10), 1620-1628.
[7] Watanabe, T., Ono, T., & Kimura, Y. (2011). Continuous fabrication of monodisperse polylactide microspheres by droplet-to-particle technology using microfluidic emulsification and emulsion–solvent diffusion. Soft Matter, 7(21), 9894-9897.
[8] Zhang, A. L., & Zha, Y. (2012). Fabrication of paper-based microfluidic device using printed circuit technology. Aip Advances, 2(2), 1.
[9] Takehara, H., Jiang, C., Uto, K., Ebara, M., & Ichiki, T. (2013). Novel microfluidic valve technology based on shape memory effect of poly (ε-caprolactone). Applied Physics Express, 6(3), 7201.
[10] Ainla, A. (2012). Hydrodynamic flow confinement technology in microfluidic perfusion devices. Micromachines, 3(2), 442-461.

Downloads: 686
Visits: 24839

Sponsors, Associates, and Links


All published work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright © 2016 - 2031 Clausius Scientific Press Inc. All Rights Reserved.