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Systematic review of adjuvant sulfasalazine in the treatment of ulcerative colitis

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DOI: 10.23977/medsc.2022.030217 | Downloads: 31 | Views: 1062

Author(s)

Hui Zhang 1, Yi Li 2, Yujiao Xue 1, Changan Zhou 1

Affiliation(s)

1 Shaanxi University of Chinese Medicine, Xianyang 712046, Shaanxi Province, China
2 The Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang 712000, Shaanxi Province, China

Corresponding Author

Yi Li

ABSTRACT

The incidence of ulcerative colitis is concentrated in those with a high educational level such as universities. The incidence is mainly young and middle-aged, and the occupational pressure is high, such as teachers and technicians, and the incidence of ulcerative colitis is not obvious in men and women. Difference; the disease can occur at any age, but more common in young adults. Its main symptoms are stool mucus pus and blood, abdominal pain, increased stool frequency, fatigue, loose stools, poor sleep, dry mouth, cold body and cold limbs, impatience, tenesmus, etc. OBJECTIVE: This study compared mesalazine and sulfasalazine to study the systematic review of sulfasalazine in the adjuvant treatment of ulcerative colitis. Methods: A total of 62 patients admitted to the hospital were selected and divided into two groups by random number method. They were treated respectively. The treatment effect, the frequency of defecation, diarrhea, abdominal pain and the incidence of adverse reactions were compared between the two groups before and after treatment. Results: The two groups of patients were compared after treatment, and the difference was statistically significant. The results showed that by comparing and analyzing the gender, age and other basic data of the two groups of patients, the curative effect of sulfasalazine was better, and the difference was not statistically significant (P>0.05), which was comparable.

KEYWORDS

Sulfasalazine, adjunctive therapy, ulcerative colitis

CITE THIS PAPER

Hui Zhang, Yi Li, Yujiao Xue, Changan Zhou, Systematic review of adjuvant sulfasalazine in the treatment of ulcerative colitis. MEDS Clinical Medicine (2022) Vol. 3: 100-104. DOI: http://dx.doi.org/10.23977/medsc.2022.030217.

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