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Research Status of Antigen Synthesis Methods

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DOI: 10.23977/jfsst.2021.010910 | Downloads: 4 | Views: 138


Yixin Ji 1,2, Yibo Zhang 3, Haihong Xin 1,2, Tingxin Wang 1


1 College of Quality and Technical Supervision, Hebei University, Baoding, China
2 Institute of Quality and Performance Management, Hebei University, Baoding, China
3 College of stomatology, Hebei Medical University, Shijiazhuang, China

Corresponding Author

Tingxin Wang


Most haptens are small molecules compounds. Because of its small molecular mass itself alone can not induce an immune response, it is necessary to form combined with the carrier hapten-carrier protein conjugate can stimulate the body's immune response. In recent years, in-depth research has been conducted at home and abroad on the synthesis of artificial antigens and the analysis of the results. Artificial antigen synthesis technology has been applied to many fields such as food and environment, which have more or less impact on our lives. This article reviews how to select carrier protein and the coupling method of hapten and carrier in the process of artificial antigen synthesis.


Hapten, Carrier protein, Artificial antigen, Coupling


Yixin Ji, Yibo Zhang, Haihong Xin and Tingxin Wang. Research Status of Antigen Synthesis Methods. Journal of Frontiers of Society, Science and Technology (2021) 1: 68-75. DOI:


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